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** BREAST CANCER News **
No news for this category today.
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** CANCER / ONCOLOGY News **
A Practical Method To Deal With Differential Motion Of Target And OAR During Image Guided Radiotherapy
http://www.medicalnewstoday.com/articles/122379.php
Current image guided radiotherapy systems provide efficient on-line correction of target positioning. Significant motion, however, can occur between target and organs-at-risk (OARs), for instance for lung tumours (baseline shifts).
Introducing Pareto Front Evaluation As A Concept For Objective Evaluation Of Inverse Planning And Delivery Techniques
http://www.medicalnewstoday.com/articles/122378.php
Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other.
Quantifying The Robustness Of IMRT Treatment Plans From A Statistical Optimization Model To Account For Organ Deformation
http://www.medicalnewstoday.com/articles/122377.php
Organ movement remains the biggest challenge in prostate cancer treatment. Computerised tomography (CT scans) provide incomplete information about movement of the prostate. To address this problem, a statistical model of motion as been created using Principle Component Analysis (PCA).
DMLC Motion Tracking Of Moving Targets For Intensity Modulated Arc Therapy Treatment
http://www.medicalnewstoday.com/articles/122375.php
Intensity modulated arc therapy offers great advantages by delivering a fast and highly conformal treatment. However, moving targets represent a major challenge. By monitoring a moving target it is possible to make the beam follow the motion, shaped by a Dynamic MLC (DMLC).
Impact Of Fractionated Irradiation On Tumor Microenvironment In Human Squamous Cells Carcinomas (hSCC) In Nude Mice
http://www.medicalnewstoday.com/articles/122372.php
Evidence shows that pre-treatment tumour hypoxia correlates with poor radiotherapy outcome. Using an hypoxia marker, pimonidazole, it has been shown that biochemical hypoxia in tumours before treatment correlates with local control after radiotherapy.
Sensing Of DNA-dsbs Under Continual Hypoxia
http://www.medicalnewstoday.com/articles/122368.php
Intracellular hypoxia has been linked to genetic instability, tumour progression and poor prognosis. Little is known about the effect of hypoxia on DNA-dsb sensing and repair. We tested whether the sensing of DNA-dsbs and chromatin biology is decreased in cells irradiated under continual hypoxic or anoxic conditions.
Caveolin-1 Contributes To Regulation Of Radiation Survival Via The B1 Integrin/AKT Signaling Axis
http://www.medicalnewstoday.com/articles/122367.php
The integral membrane protein Caveolin-1 forms small invaginations of the plasma membrane, so-called caveolae, for serving in endo-exocytosis and is involved in regulating signaling from integrins and receptor-tyrosine kinases.
Radiobiology Topics At ESTRO 27 (European Society For Therapeutic Radiology And Oncology)
http://www.medicalnewstoday.com/articles/122366.php
More biology abstracts were submitted to this year's ESTRO meeting than ever before. This is very encouraging for European radiobiology, particularly for "translational" biological research on radiation effects aimed at improving radiotherapy.
Dose-Volume For Ionising Radiation To The Rectum And Sigmoid Decides The Prevalence Of Unexpected Defecation In Clothing
http://www.medicalnewstoday.com/articles/122362.php
Long-term gynaecological cancer survivors stand a considerable risk of unexpected defecation in clothing, after curative radiotherapy. We investigated the relationship between radiation-dose and irradiated volume of risk-organs and the prevalence of this difficult adverse effect.
Two-Year Results From A Swedish Study On Conventional Versus Accelerated Radiotherapy In Head And Neck Squamous Cell Carcinoma (ARTSCAN)
http://www.medicalnewstoday.com/articles/122358.php
It is known that in radiotherapy prolonging the overall treatment time beyond seven weeks leads to less effective treatment of e.g. cancers of the head and neck. Consequently, the aim of several studies has been to evaluate the effect of shortened treatment time by "accelerated fractionation" (AF).
Vaginal Brachytherapy Versus External Beam Pelvic Radiotherapy For High-Intermediate Risk Endometrial Cancer - Randomised PORTEC-2 Trial
http://www.medicalnewstoday.com/articles/122356.php
Endometrial carcinoma is the most common gynecological malignancy among postmenopausal European women. Patients with high-intermediate risk endometrial cancer (based on age, tumour stage and grade) who receive no further treatment following surgery, have an approximately 20% risk of developing a locoregional recurrence, of which 75% are located in the vagina and 25% in the pelvic lymph nodes.
Do We Need More Intense Radiotherapy In Locally Advanced Head And Neck Cancers? Results From A Large Randomized Trial From The GORTEC
http://www.medicalnewstoday.com/articles/122355.php
The objective of the trial was to test new therapeutic approaches in patients with locally advanced head and neck carcinomas. These cancers are generally treated with conventional radiotherapy (RT), con¬comitant with chemotherapy (CT), which is a well accepted standard therapeutic approach.
Clinical Topics At ESTRO 27 (European Society For Therapeutic Radiology And Oncology)
http://www.medicalnewstoday.com/articles/122354.php
Radiation oncologists and other clinicians have comprised the majority of ESTRO's membership since it was founded in 1980. Over those 28 years cancer care has improved dramatically. The pace of change is arguably greater now than ever before, with new imaging modalities, medical informatics, genomics, targeted molecular therapies and in¬dividualized therapies.
New HPV-DNA Test To Screen Women In Developing Countries For Cervical Precancerous Disease Has 90% Success Rate
http://www.medicalnewstoday.com/articles/122353.php
Results of a study to determine the accuracy of a new rapid screening test for HPV (human papillomavirus), created specifically for use in the developing world, have shown it to be 90% accurate in detecting precancerous cervical disease when tested on a group of women in Shanxi province, eastern China.
FDA Approves GE Healthcare's AdreView (Iobenguane I 123 Injection) Diagnostic Agent For Detecting Neuroendocrine Tumors In Children, Adults
http://www.medicalnewstoday.com/articles/122327.php
GE Healthcare, a unit of General Electric Company (NYSE:GE), announced that the Food and Drug Administration (FDA) has approved AdreView™ (Iobenguane I 123 Injection), a molecular imaging agent for the detection of rare neuroendocrine tumors in children and adults.
Elekta Announces Availability Of Elekta Infinity With VMAT Technology For Fast, More Precise Treatment Of Cancer
http://www.medicalnewstoday.com/articles/122325.php
Elekta, pioneering significant innovations and clinical solutions for cancer and neurological conditions, announced new product offerings from the Elekta Group. Topping the list of innovations is Elekta Infinity; the company's most advanced digital linear accelerator, now available to customers in the United States.
Is OB Glue Paste Technique Ideal To Establish Nude Mouse Transplantation Model?
http://www.medicalnewstoday.com/articles/122302.php
Establishment of human gastric cancer nude mouse transplantation models has undergone three representative stages: subcutaneous transplantation of cell suspension, gastric wall seeding of cell suspension, and intra-gastric wall transplantation of histologically intact tissue, of which the fresh tissue orthotopic transplantation model has two types: the "suture method"and the "gastric bursa method".
Effective Chemoradiotherapy Method For Pancreatic Cancer
http://www.medicalnewstoday.com/articles/122265.php
Pancreatic cancer is the fifth most common cause of cancer death in Japan. The prognosis is extremely poor because it is difficult to detect this disease in the early stages and also the postoperative incidence of recurrence is still high, and we have not had any effective treatment for inoperable patients.
What Contributes To The Biological Behaviors Of Gastric Carcinomas?
http://www.medicalnewstoday.com/articles/122257.php
Gastric carcinoma is one of the most frequent malignant tumors in the world. The gastric carcinoma cell with fibroblastic pattern which intracellular adhesion was decreased showed active mobility and invasiveness, which indicated that the EMT was placed.
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** CERVICAL CANCER / HPV VACCINE News **
Phase II Study Of PET Image-Guided IMRT To 60 Gy For Positive Para-Aortic Lymph Nodes In Cervix Cancer
http://www.medicalnewstoday.com/articles/122361.php
The purpose of this research was to evaluate the feasibility and toxicity of Positron emission tomography (PET) Image-Guided irradiation (IMRT) of FDG-PET positive pelvic and para-aortic lymph nodes to 60 Gy in patients with carcinoma of the cervix.
MRI Assessment Of Tumour Spread And Response For Image Guided Cervical Cancer Brachytherapy
http://www.medicalnewstoday.com/articles/122360.php
The treatment of choice for patients with locally advanced cervix cancer is a combination of external beam radiation therapy (EBRT), concomitant chemotherapy and brachytherapy (BT). An image guided approach (IGBT) using magnetic resonance imaging (MRI) is becoming state of the art for the BT component of this treatment .
New HPV-DNA Test To Screen Women In Developing Countries For Cervical Precancerous Disease Has 90% Success Rate
http://www.medicalnewstoday.com/articles/122353.php
Results of a study to determine the accuracy of a new rapid screening test for HPV (human papillomavirus), created specifically for use in the developing world, have shown it to be 90% accurate in detecting precancerous cervical disease when tested on a group of women in Shanxi province, eastern China.
NPR's 'Morning Edition' Examines Parents' Concerns About HPV Vaccine
http://www.medicalnewstoday.com/articles/122268.php
<BR />NPR's "<A href="http://www.npr.org/templates/story/story.php?storyId=94730980&ft=1&f=1007" target=_new>Morning Edition</A>" on Thursday examined how uneasiness among some parents about having their adolescent girls receive the human papillomavirus vaccine, which is recommended for girls ages 11 to 12, is contributing to low vaccination rates.
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** COLORECTAL CANCER News **
ICT And Dose Intensification Of The Radiation Boost In Locally Advanced Anal Canal Carcinoma
http://www.medicalnewstoday.com/articles/122357.php
Anal cancer is rare but the incidence is increasing, associated with HPV infection. Cure is possible in the majority of patients with the preservation of the anus and a functional anal sphincter.
ERBITUX(R) Now Available In Japan For Use In Treating Patients With Advanced Colorectal Cancer
http://www.medicalnewstoday.com/articles/122329.php
ImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, announced that ERBITUX® (cetuximab) has been commercially launched in Japan for use in treating patients with advanced or metastatic colorectal cancer (mCRC).
Gut Bacterium Linked To Colon Cancer
http://www.medicalnewstoday.com/articles/122314.php
US scientists found that a common bacterium found in the gut could play a role in the development of colon cancer by producing a fermentation byproduct that damages DNA and affects signalling pathways used by colon cancer cells and the immune system.
Rectal Carcinoma: What Induces Local Recurrence?
http://www.medicalnewstoday.com/articles/122301.php
It is well known that local recurrence is the most important prognostic factor of rectal carcinoma. However, even after undergoing radical resection of primary tumors and lymph nodes, about 4%-50% of patients with rectal carcinoma were reportedly with local recurrence.
Is Local Anesthetic Wound Infusion Following Laparotomy Effective For Colorectal Surgery?
http://www.medicalnewstoday.com/articles/122266.php
Although suboptimal postoperative pain control is associated with cardiovascular, respiratory and gastrointestinal complications, many multimodal regimens for analgesia following major colorectal laparotomy provide inadequate pain relief.
A New Diagnostic Tool For Colorectal Cancers Prognosis
http://www.medicalnewstoday.com/articles/122258.php
To analyze the clinical significance of BAMBI, authors studied its expression in CRC using immunohistochemical staining. They show that BAMBI overexpression is correlated with aggressive tumor phenotypes and predicts tumor recurrence and cancer-related death in CRC.
Strong Association Found Between Prevalence Of Low White Blood Count And Women Of African Descent
http://www.medicalnewstoday.com/articles/122252.php
Researchers from Columbia University Mailman School of Public Health and the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, have found a strong association between women of African descent from the U.
The Sign For Progression Of Colorectal Carcinoma
http://www.medicalnewstoday.com/articles/122248.php
The process of tumor invasion and metastasis is associated with alterations in the functions of several adhesion molecules. In general, tumor cells lose their capacity for normal adherence, which facilitates their detachment from their site of origin.
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** LUNG CANCER News **
Motion-compensated Cone-beam CT For Accurate Online Assessment Of The Position Of Lung Tumours
http://www.medicalnewstoday.com/articles/122374.php
High precision radiotherapy requires accurate tumour localisation for patient positioning just prior to treatment. Respiratory motion induces artifacts in cone-beam (CB) CT images of the thorax and upper abdomen which can prevent an accurate localisation of tumours.
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** LYMPHOMA / LEUKEMIA News **
No news for this category today.
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** PROSTATE / PROSTATE CANCER News **
American Urological Association Releases Best Practice Statement On Cryosurgery For The Treatment Of Localized Prostate Cancer
http://www.medicalnewstoday.com/articles/122417.php
When the American Urological Association (AUA) guideline on the Management of Clinically Localized Prostate Cancer: 2007 Update was published, insufficient information was available to include cryosurgery in the data analysis.
Urinary Toxicity After Radiotherapy For Prostate Cancer: Dose Maps To Identify Dose-effect Relationships
http://www.medicalnewstoday.com/articles/122369.php
After external radiotherapy for prostate cancer, patients can suffer from long-term urinary problems, including incontinence and obstruction. Many studies have investigated the relationship between urinary problems and the radiation dose the bladder was exposed to, as estimated during the planning of the treatment.
Long-Term Chronic Toxicity Of A Dose Escalating HDR-BT Boost Combined With Pelvic EBRT For Intermediate And High Risk Prostate Cancer
http://www.medicalnewstoday.com/articles/122364.php
The results of conventional external-beam radiation therapy (EBRT) in intermediate/high-risk prostate cancer patients have been poor. Since a dose-response relationship has been established in these subgroups of patients, a dose-escalation trial using a combination of EBRT and high-dose-rate (HDR) brachytherapy boost (BT) was started at William Beaumont Hospital in 1991.
Long Term Follow-up Demonstrates The Correlation Between D90 And Outcomes For I-125 Seed Implant Monotherapy For Localised Prostate Cancer
http://www.medicalnewstoday.com/articles/122363.php
Prostate cancer is one of the most common cancers in men. One treatment option for those with early disease is prostate brachytherapy, where small radioactive sources are implanted directly into the gland.
Nymox NX-1207 Data Presented At American Urological Association Meetings In San Diego And Santa Ana Pueblo, New Mexico
http://www.medicalnewstoday.com/articles/122328.php
Nymox Pharmaceutical Corporation (NASDAQ:NYMX) is pleased to announce two separate presentations of new data by independent clinical investigators involved in U.S. clinical trials of NX-1207, Nymox's investigational drug for benign prostatic hyperplasia (BPH).
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1 comment:
Very interesting blog. Its an informative topic.
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