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** BREAST CANCER News **
Can The Metastatic Lymph Node Ratio Predict Survival Rate In Gastric Cancer Patients?
http://www.medicalnewstoday.com/articles/122855.php
Previous studies have proven that the MLR is an excellent predictor for survival outcome in patients with colon cancer, pancreatic cancer, breast cancer and other carcinomas. Some related studies on gastric cancer also found the potential of the MLR on prognostic evaluation.
Breast Cancer Treatment Can Be Undermined By The Dietary Supplement Genistein
http://www.medicalnewstoday.com/articles/122803.php
Women taking aromatase inhibitors to treat breast cancer or prevent its recurrence should think twice before also taking a soy-based dietary supplement, researchers report.Genistein, a soy isoflavone that mimics the effects of estrogen in the body, can negate the effectiveness of aromatase inhibitors, which are designed to reduce the levels of estrogens that can promote tumor growth in some types of breast cancer.
Relapse In Early Breast Cancer Patients Following Endocrine Therapy, Prediced By New Model
http://www.medicalnewstoday.com/articles/122781.php
Researchers have developed and validated a model that predicts relapse in women with stage 2 or 3 breast cancer who have been treated with endocrine therapy prior to surgical removal of the tumor, according to a study published online September 23 in the Journal of the National Cancer Institute.
Hormone Therapy Safe For Postmenopausal BRCA Mutation Carriers According To Observational Study
http://www.medicalnewstoday.com/articles/122780.php
The use of hormone therapy was associated with a reduced risk of breast cancer in postmenopausal women who carry BRCA mutations, according to a case-control study published online September 23 in the <i>Journal of the National Cancer Institute.
Breast Cancer Treatment Resistance Linked To Signaling Pathway
http://www.medicalnewstoday.com/articles/122746.php
Activation of the Src signaling pathway may cause resistance to standard medical treatment in some patients with breast cancer, and inhibition of this pathway holds the potential to overcome that resistance, according to data presented here at the American Association for Cancer Research Molecular Diagnostics in Cancer Therapeutic Development meeting.
Determining Treatment Of Breast Cancer Patients Using New Predictive Tool
http://www.medicalnewstoday.com/articles/122724.php
A new predictive measurement, called a PEPI score, could bring good news to many women diagnosed with early stage breast cancer - a low PEPI (preoperative endocrine prognostic index) score could show that they have little risk of relapse and can safely avoid chemotherapy after surgery.
News From The Journal Of The National Cancer Institute, Sept. 23
http://www.medicalnewstoday.com/articles/122723.php
<b>Breast Cancer Incidence Rate Predicted to Climb Dramatically in China</b>The breast cancer incidence in China is predicted to climb from the current rate of 10 cases per 100,000 women aged 55+ years to more than 100 cases per 100,000 women in 2021.
Monogram And Dana-Farber Cancer Institute Initiate Evaluation Of HERmark(TM) Breast Cancer Assay In Metastatic Breast Cancer
http://www.medicalnewstoday.com/articles/122641.php
Monogram Biosciences, Inc. (Nasdaq: MGRM) announced that it has initiated a study, in collaboration with the Dana-Farber Cancer Institute (DFCI), to evaluate Monogram's HERmark(TM) Breast Cancer Assay in metastatic breast cancer.
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** CANCER / ONCOLOGY News **
Racial Disparities Decline For Cancer In Missouri
http://www.medicalnewstoday.com/articles/122896.php
Cancer death rates in the United States are highest among African Americans, but a new report shows that in Missouri the disparity in cancer incidence and death between African Americans and whites is declining.
Why Does Gecko, A Chinese Traditional Medicine, Have Anti-Tumor Effects?
http://www.medicalnewstoday.com/articles/122892.php
The incidence and mortality of tumors keep ascending all over the world. Gecko had a positive effect on malignant tumors in clinical practice reports. However, there was no study on the pharmacological studies of Gecko and its mechanisms of anti-tumor action remained unclear.
Is Endoscopic Ultrasound A Better Choice For Staging Of Gastric Cancers?
http://www.medicalnewstoday.com/articles/122890.php
Puli et al carried out a search to evaluate the accuracy of EUS in staging gastric cancers, and their results were published in the <i>World Journal of Gastroenterology.</i>Puli identified 1620 reference articles and 376 relevant articles were selected and reviewed.
Intraperitoneal Metastasis After Spontaneous Rupture Of Hepatocellular Carcinoma
http://www.medicalnewstoday.com/articles/122882.php
Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. It is usually manifested in the 6th and 7th decade of life. Extrahepatic metastases are seen in 64% of patients with HCC.
The Effect Of Curcuma Wenyujin On Human HepG2 Cancer Cells
http://www.medicalnewstoday.com/articles/122877.php
Hepatocellular carcinoma (HCC) is the fifth most common cancer with more than 1 million fatalities occurring annually worldwide. Nowadays in China, the essential oil of Curcuma wenyujin (CWO) has been used as an injection to cure paediatric diseases such as acute upper respiratory infections, viral myocarditis and acute pneumonia.
Is Mirtazapine And Fluoxetine Helpful In Treating Pancreatic Cancer?
http://www.medicalnewstoday.com/articles/122860.php
The treatment of pancreatic cancer remains a great challenge. The majority of patients with pancreatic cancer developed major depression. Antidepressant treatment has been accepted as one of the new strategies in cancer adjuvant therapy.
A New Therapeutic Option For Human Hepatocyte Cancer
http://www.medicalnewstoday.com/articles/122840.php
Tumors that are p53-impaired may be particularly suitable to parvovirus H-1-induced therapy. Although the p53 deficiency in tumors may induce resistance to chemotherapeutic agents, this will not affect the tumor cell susceptibility to H-1 PV-induced oncolytic infections.
Delivering Toxic Genes To Effectively Kill Pancreatic Cancer Cells
http://www.medicalnewstoday.com/articles/122808.php
A research team, led by investigators at the Department of Surgery at Jefferson Medical College of Thomas Jefferson University and the Kimmel Cancer Center at Jefferson, has achieved a substantial "kill" of pancreatic cancer cells by using nanoparticles to successfully deliver a deadly diphtheria toxin gene.
Long-Term Cancer Survivors At Greater Risk Of Severe Stress
http://www.medicalnewstoday.com/articles/122766.php
Long-term survivors of adult cancers are almost twice as likely to report psychological distress severe enough to cause moderate to serious problems functioning in social, work or school situations, compared to the general population, according to a large, national study presented September 24, 2008, at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.
UNC Charlotte To Evaluate Potential Adjuvant Activity Of ImmuneRegen's Viprovex(R) With Cancer Vaccine
http://www.medicalnewstoday.com/articles/122754.php
ImmuneRegen BioSciences, Inc., a wholly owned subsidiary of IR BioSciences Holdings, Inc. (OTCBB: IRBS), today announces a collaborative relationship with the University of North Carolina at Charlotte to evaluate ImmuneRegen's Viprovex as a possible cancer-vaccine adjuvant.
Massage Therapy May Have Immediate Positive Effect On Pain And Mood For Advanced Cancer Patients
http://www.medicalnewstoday.com/articles/122731.php
A new study found that massage therapy may have immediate benefits on pain and mood among patients with advanced cancer. The study, sponsored by the Institute of Medicine and the National Institutes of Health, was a randomized trial of 380 advanced cancer patients at 15 U.
Amplified Gene In Cells Found In Urine Reveals Presence Bladder Cancer
http://www.medicalnewstoday.com/articles/122726.php
Counting the copies of a specific gene in cells gathered from a urine sample may provide a simple, noninvasive way to detect bladder cancer, a team led by researchers at The University of Texas M.
News From The Journal Of The National Cancer Institute, Sept. 23
http://www.medicalnewstoday.com/articles/122723.php
<b>Breast Cancer Incidence Rate Predicted to Climb Dramatically in China</b>The breast cancer incidence in China is predicted to climb from the current rate of 10 cases per 100,000 women aged 55+ years to more than 100 cases per 100,000 women in 2021.
New Instrument Can Quickly Examine Multiple Proteins In A Single Cancer Sample
http://www.medicalnewstoday.com/articles/122717.php
Researchers have demonstrated a new instrument that makes it possible to detect and quantify multiple different clinically important proteins in a single tumor sample using conventional staining.
Scientists Develop New, More Sensitive Nanotechnology Test For Chemical DNA Modifications
http://www.medicalnewstoday.com/articles/122716.php
Researchers at The Johns Hopkins University School of Medicine in Baltimore have developed a novel test to screen for chemical modifications to DNA known as methylation. The technology potentially could be used both for early cancer diagnoses and for assessing patients' response to cancer therapies.
Research Into Deadly Cancer In Dogs May Also Have Human Applications
http://www.medicalnewstoday.com/articles/122712.php
A new study jointly conducted by Oregon State University College of Veterinary Medicine and the Oregon Health & Science University Cancer Institute may one day help not only our canine friends with cancer, but also people with the human form of the disease.
Macmillan Cancer Support Response To Gordon Brown's Speech, UK
http://www.medicalnewstoday.com/articles/122699.php
Responding to Gordon Brown's announcement that prescriptions charges are to be scrapped for cancer patients in England Ciaran Devane, Chief Executive at Macmillan Cancer Support said: "We are absolutely delighted the Government has listened to us.
Non-Hodgkin's Lymphoma - Recruitment Completed In Ofatumumab NHL Pivotal Study
http://www.medicalnewstoday.com/articles/122691.php
Genmab A/S (OMX: GEN) announced it has completed recruitment of patients in the pivotal Phase III study of ofatumumab (HuMax-CD20(R)) in rituximab refractory follicular non-Hodgkin's lymphoma (NHL).
Skin Disorder Vitiligo Could Yield Clues In Fight Against Melanoma
http://www.medicalnewstoday.com/articles/122662.php
About 1 million Americans suffer a skin disorder called vitiligo, which causes unsightly white patches on the face, hands and other parts of the body.A Loyola University Hospital researcher has won a five-year, $1.
Methylation Levels Key To Glioblastoma Survival
http://www.medicalnewstoday.com/articles/122650.php
A new study analyzing gene expression among patients with glioblastomas has found that not all of the common, deadly brain tumors appear the same upon closer examination.The research, directed by scientists at The University of Texas M.
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** CERVICAL CANCER / HPV VACCINE News **
HPV Test Found To Be 90% Effective In Detecting Cervical Cancer In Rural Area Of China, Study Finds
http://www.medicalnewstoday.com/articles/122678.php
<BR />A new low-cost, rapid cervical cancer screening test, called careHPV, was 90% accurate in identifying women who have CIN2+, which includes moderate or severe cervical disease and cancer, according to a <A href="http://www.
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** COLORECTAL CANCER News **
A Promising Possibility For The Treatment Of The Esophageal Carcinoma
http://www.medicalnewstoday.com/articles/122893.php
Recent work demonstrates that GSK-3 beta is involved in the process of tumorigenesis, and inhibition of the expression and activity of GSK-3 beta attenuates cell proliferation and causes apoptosis in colorectal, pancreatic and ovarian cancer cells.
Immunohistochemical Localization Of Glutathione-S-Transferase-Pi In Human Colorectal Polyps
http://www.medicalnewstoday.com/articles/122880.php
Specific molecular forms of GST are known to be expressed in preneoplastic cells, and have been known to participate in their resistance to drugs. GST-pi are present in most epithelial tissues of the human gastrointestinal tract.
Can The Metastatic Lymph Node Ratio Predict Survival Rate In Gastric Cancer Patients?
http://www.medicalnewstoday.com/articles/122855.php
Previous studies have proven that the MLR is an excellent predictor for survival outcome in patients with colon cancer, pancreatic cancer, breast cancer and other carcinomas. Some related studies on gastric cancer also found the potential of the MLR on prognostic evaluation.
A Mixed Rectal Tumor And Adenocarcinoma: A Case Report
http://www.medicalnewstoday.com/articles/122854.php
Prof. John M. Carethers reported an unusual case of a mixed rectal tumor containing a superficial tubulovillous adenoma with deeper areas of high grade malignant spindle cells and an invasive adenocarcinoma.
Is Bcl-2 Protein A Major Obstacle In Treating Colorectal Carcinoma?
http://www.medicalnewstoday.com/articles/122834.php
Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC). Moreover, apoptosis resistance of carcinoma cells provides an explanation for low response rates in patients with advanced cancer receiving chemotherapy.
Study Finds That Quality Of Colon Cancer Surgery Is An Important Factor In Patient Survival
http://www.medicalnewstoday.com/articles/122675.php
A research study has suggested for the first time that the quality of surgery for colon cancer is associated with patient survival. UK researchers found marked variability in the plane of surgery - the directions in which dissection is carried out - in operations to remove colon cancers, with direct impact on survival, when they analysed the tissue removed during cancer surgery in nearly 400 patients.
The Facts Hispanics Need To Know About Colon Cancer
http://www.medicalnewstoday.com/articles/122648.php
Each year approximately 150,000 people in the United States are diagnosed with colon cancer and nearly 50,000 will die from the disease. All men and women are at risk for colon cancer. However, because of disproportionate screening rates, minorities, including Hispanics, are more likely to be diagnosed with colon cancer in advanced stages.
Medicsight Announces American College Of Radiology Imaging Network ("ACRIN") Trial Shows CT Colonography Now An Option For Colon Cancer Screening
http://www.medicalnewstoday.com/articles/122637.php
Medicsight PLC, a subsidiary of MGT Capital Investments, Inc. (Amex: MGT), and an industry leader in the development of Computer-Aided Detection (CAD) and image analysis software, announced that the National U.
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** LUNG CANCER News **
Radioactive Seed Therapy Shows Significant Reduction In Lung Cancer Recurrence
http://www.medicalnewstoday.com/articles/122632.php
Radiation oncologists at Allegheny General Hospital (AGH) in Pittsburgh will report to the American Society for Therapeutic Radiology and Oncology (ASTRO) in Boston that a newer, minimally invasive approach to treating high risk patients with Stage I non-small cell lung carcinoma (NSCLC) may significantly reduce the risk of local disease recurrence.
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** LYMPHOMA / LEUKEMIA News **
A Novel Technique For Detection Of Tumor Lymphangiogenesis
http://www.medicalnewstoday.com/articles/122884.php
Lymphangiogenesis, the formation of new lymphatic vessels, has become a new research frontier. There is a crucial need for noninvasive methods to evaluate lymphangiogenesis in situ. However, to the best of our knowledge, lymphosonography about the tumour lymphangiogenesis with percutaneous hepatic injection of ultrasound contrast material was not reported before.
DKMS And The Leukemia & Lymphoma Society's New York City Chapter Announce Partnership
http://www.medicalnewstoday.com/articles/122745.php
DKMS, the world's largest bone marrow donor center, and The Leukemia & Lymphoma Society's New York City Chapter will team up at this year's Light The Night Walk(R) to pay homage to patients battling cancer and to recruit bone marrow donors needed to give hope to more patients suffering from life-threatening blood diseases, such as leukemia and lymphoma.
Epstein-Barr Virus Predicts Outcome In Nasopharyngeal Carcinoma
http://www.medicalnewstoday.com/articles/122744.php
Researchers in Hong Kong report that testing patient blood for DNA from Epstein-Barr virus (EBV) during treatment for nasopharyngeal carcinoma effectively predicts clinical outcome. A biomarker test like this, when perfected, could identify patients whose treatment could be intensified after a month or so of standard therapy as well as those who might benefit from lighter treatment.
Non-Hodgkin's Lymphoma - Recruitment Completed In Ofatumumab NHL Pivotal Study
http://www.medicalnewstoday.com/articles/122691.php
Genmab A/S (OMX: GEN) announced it has completed recruitment of patients in the pivotal Phase III study of ofatumumab (HuMax-CD20(R)) in rituximab refractory follicular non-Hodgkin's lymphoma (NHL).
Recruitment Completed In Ofatumumab NHL Pivotal Study
http://www.medicalnewstoday.com/articles/122631.php
Genmab A/S (OMX: GEN) announced it has completed recruitment of patients in the pivotal Phase III study of ofatumumab (HuMax-CD20(R)) in rituximab refractory follicular non-Hodgkin's lymphoma (NHL).
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** PROSTATE / PROSTATE CANCER News **
Breathing During Radiation Studied By OHSU Cancer Institute Researchers
http://www.medicalnewstoday.com/articles/122894.php
Oregon Health & Science University researchers have determined exactly how much breathing affects prostate movement during radiation treatment.The results of this research were presented at the 50th annual American Society for Therapeutic Radiology and Oncology in Boston.
Nymox's NX-1207 For The Treatment Of Benign Prostatic Hyperplasia In Phase 3 Program
http://www.medicalnewstoday.com/articles/122791.php
Nymox Pharmaceutical Corporation (NASDAQ: NYMX) is pleased to announce that results from the most recently completed clinical studies of NX-1207, the Company's investigational drug for the treatment of benign prostatic hyperplasia (BPH), will be presented on Thursday, September 25 at the 82nd Annual Meeting of the North Central Section of the American Urological Association being held in Chicago.
For High-Risk Prostate Cancer Patients, New Tool Helps Physicians Tailor Hormone Therapy
http://www.medicalnewstoday.com/articles/122778.php
Using one of the largest databases of prostate cancer outcomes in the United States, Fox Chase Cancer Center researchers have developed a prediction tool that uses a patient's clinical information to estimate the benefit of adding androgen deprivation therapy of various durations to radiation therapy.
When/If To Start Hormones For Prostate Cancer Patients Whose PSA Rises After Radiation: New Study
http://www.medicalnewstoday.com/articles/122776.php
A new Fox Chase Cancer Center study suggests men with early stage prostate cancer treated with radiation therapy should begin hormone therapy immediately if their PSA level rises quickly and doubles within six months at any time after treatment.
Prostate Cancer: Hormone Therapy Before Radiation Seed Implants
http://www.medicalnewstoday.com/articles/122769.php
Men over 70 years of age with early-stage prostate cancer have 20 percent higher mortality if they are treated first with hormone therapy before being treated with radiation seed implants (brachytherapy), compared to men who are treated with brachytherapy alone, according to the largest cohort study of its kind presented September 23, 2008, at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.
New Web Site Helps Doctors And Prostate Cancer Patients Make Better Treatment Choices
http://www.medicalnewstoday.com/articles/122767.php
Doctors have created a free online computer tool, the CaP Calculator, that provides cancer specialists access to the latest prostate cancer research and helps them better individiualize each patient's treatment options, according to a study presented in a scientific session on September, 23, 2008, at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.
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