Tuesday, November 18, 2008

Medical News Today News Alert

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** BREAST CANCER News **

Dangerous 'Two-Faced' Protein Crucial To Breast Cancer Spread And Growth Identified By Mayo Researchers
http://www.medicalnewstoday.com/articles/129838.php
Two critical properties of cancer cells are their ability to divide without restraint and to spread away from the primary tumor to establish new tumor sites. Now, researchers from the Mayo Clinic campus in Florida have found a protein they say acts as a deadly master switch, both freeing cancer cells from a tumor while ramping up new growth.

Breast Cancer Common Among Women With Family History But Without BRCA1 Or BRCA2
http://www.medicalnewstoday.com/articles/129801.php
New data presented at the American Association for Cancer Research's Seventh Annual International Frontiers in Cancer Prevention Research meeting outlines new data, which assesses breast cancer risk among women with a strong family history of breast cancer, but without a BRCA1 or BRCA2 mutation.

Latinas More Likely To Regret Breast Cancer Treatment Decisions, USA
http://www.medicalnewstoday.com/articles/129782.php
Latina women who prefer speaking Spanish are more likely than other ethnic groups to express regret or dissatisfaction with their breast cancer treatment, according to a new study by researchers at the University of Michigan Comprehensive Cancer Center.

Psychological Interventions Associated With Breast Cancer Survival
http://www.medicalnewstoday.com/articles/129778.php
A new study finds that breast cancer patients who participate in intervention sessions focusing on improving mood, coping effectively, and altering health behaviors live longer than patients who do not receive such psychological support.

Studies To Examine Factors Behind Racial Disparities In Breast, Colon Cancers
http://www.medicalnewstoday.com/articles/129775.php
The following summarizes articles about two cancer studies that examine racial disparities.<ul><li class="AdvisoryBullet">Breast cancer: Researchers from the University of North Carolina's <a href="http://cancer.

Sanofi-Aventis Pharma S.A. Withdraws Its Application For An Extension Ofindication For Taxotere And Docetaxel Winthrop (docetaxel)
http://www.medicalnewstoday.com/articles/129727.php
The European Medicines Agency (EMEA) has been formally notified by Sanofi-Aventis Pharma S.A. of its decision to withdraw its application for an extension of indication for the centrally authorised medicines Taxotere (docetaxel) 20 mg/0.

Researchers Find Clue To Stopping Breast Cancer Metastasis
http://www.medicalnewstoday.com/articles/129711.php
If scientists knew exactly what a breast cancer cell needs to spread, then they could stop the most deadly part of the disease: metastasis. New research from the University of North Carolina at Chapel Hill School of Medicine takes a step in that direction.

Study: Psychological Help Improves Breast Cancer Survival
http://www.medicalnewstoday.com/articles/129683.php
You've heard the saying 'mind over matter.' Now a new study gives that phrase some scientific backing. Researchers have learned that giving breast cancer patients psychological support along with their medical treatment can dramatically improve their odds of beating the disease.

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** CANCER / ONCOLOGY News **

New Biomarkers For Brain Tumor Discovered
http://www.medicalnewstoday.com/articles/129914.php
Researchers in the US and The Netherlands have discovered that cancer cells from a deadly type of human brain tumor called glioblastoma release tiny sacs containing proteins that traverse the brain-blood barrier and contain genetic material that could be used as biomarkers in new diagnostic tools and perhaps as new targets for treatments too.

Thallion Initiates Enrollment In Phase II Metastatic Melanoma Trial
http://www.medicalnewstoday.com/articles/129890.php
Thallion Pharmaceuticals Inc. (TSX:TLN) today announced that the first patient has been enrolled in its Phase II trial evaluating TLN-232 as a treatment for metastatic melanoma in patients who have failed one prior therapy.

In Vivo Model For Human Brain Cancer (Human Glioblastoma GBM) For Drug Discovery Applications Introduced By Celprogen
http://www.medicalnewstoday.com/articles/129880.php
Celprogen Inc., a Global leader in the Stem Cell Research and Therapeutics industry for development of stem cell technologies in regenerative medicine, today announced that they have successfully validated an in vivo model system for testing efficacy of cancer drugs and also novel drug candidates for Human Glioblastoma.

Scientists Find A Trigger To Aggressive Bowel Cancer
http://www.medicalnewstoday.com/articles/129867.php
Cancer Research UK scientists have shown how bowel cancer can become aggressive, according to research published in <i>Nature Genetics*</i>. The researchers, based in the Cardiff School of Biosciences, Cardiff University and at Cancer Research UK's Beatson Institute in Glasgow found that a tumour suppressor protein called Pten is critical in stopping tumours from growing in mice.

Type 1 Diabetes Prevented, Reversed By Two Cancer Drugs, UCSF Study Shows
http://www.medicalnewstoday.com/articles/129861.php
Two common cancer drugs have been shown to both prevent and reverse type 1 diabetes in a mouse model of the disease, according to research conducted at the University of California, San Francisco.

CAPHOSOL Results In Minimal Oral Mucositis And Pain In Head/neck Cancer Patients
http://www.medicalnewstoday.com/articles/129856.php
New data show that CAPHOSOL&reg; (www.ca<a href="http://www.caphosol.com" target="_blank" rel="nofollow">http://www.caphosol.com</a>phosol.com), an advanced electrolyte solution, results in low rates of oral mucositis and pain in patients with head and neck (HN) cancer who are undergoing chemotherapy and radiation therapy.

Breaking BubR1 Mimics Genetic Shuffle Seen In Cancer Cells
http://www.medicalnewstoday.com/articles/129837.php
A study of how one protein enzyme, BubR1, helps make sure chromosomes are equally distributed during mitosis might explain how the process of cell division goes so awry in cancer, according to researchers from Fox Chase Cancer Center.

Kidney Cancer Risk Could Be Increased By Genes Associated With Fat Metabolism
http://www.medicalnewstoday.com/articles/129804.php
A team of international scientists has identified three genes associated with the body's processing of fats that may increase susceptibility to kidney cancer. The findings were presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.

Genetic 'signature' In Healthy Liver Cells Predicts Risk Of Liver Cancer Recurrence
http://www.medicalnewstoday.com/articles/129790.php
Researchers have found a gene 'signature' - a specific set of genes - in the healthy, noncancerous cells in the liver of people who have had liver cancer that is associated with better chances of survival and a second gene signature associated with late cancer recurrence, in an international study that has shown for the first time that tissue samples preserved by traditional methods can be used for genetic analysis.

3 Esophageal, Stomach Cancer Subtypes Linked To Smoking; 1 Associated With Alcohol Use
http://www.medicalnewstoday.com/articles/129789.php
Researchers who have been following the health of more than 120,000 residents of the Netherlands for more than two decades have found that smoking is associated with two forms of esophageal cancer as well as a form of stomach cancer, and that drinking alcohol is strongly linked to one form of esophageal cancer.

Latinas More Likely To Regret Breast Cancer Treatment Decisions, USA
http://www.medicalnewstoday.com/articles/129782.php
Latina women who prefer speaking Spanish are more likely than other ethnic groups to express regret or dissatisfaction with their breast cancer treatment, according to a new study by researchers at the University of Michigan Comprehensive Cancer Center.

Silence On Drug Options "distresses" Cancer Patients
http://www.medicalnewstoday.com/articles/129748.php
Cancer patients want their oncologists to be more up-front about available drug treatments and include them in decision making, even if they cannot afford the treatment, according to new Australian research presented to the Clinical Oncolgoical Society of Australia Annual Scientific Meeting today (18/11) in Sydney.

Exercise And Sleep Reduce Women's Cancer Risk
http://www.medicalnewstoday.com/articles/129735.php
A new US study of nearly 6,000 women found that while regular exercise appeared to reduced their risk of cancer, this benefit was likely to be lost if they did not get enough sleep.The researchers presented their findings at the American Association for Cancer Research's (AACR) Seventh Annual International Conference on Frontiers in Cancer Prevention Research that is taking place in National Harbor, Maryland, this week.

EGFR-Targeting Antibody Licensed To Abbott
http://www.medicalnewstoday.com/articles/129729.php
The international Ludwig Institute for Cancer Research (LICR) has announced that one of its spin-off companies, Life Science Pharmaceuticals, has licensed its lead cancer therapy candidate, antibody 806, to pharmaceutical company Abbott.

Exercise And Rest Reduce Cancer Risk
http://www.medicalnewstoday.com/articles/129709.php
Exercise is good for more than just your waistline. A recent study presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research suggests that regular physical activity can lower a woman's overall risk of cancer but only if she gets a good night's sleep.

Three Esophageal, Stomach Cancer Subtypes Linked To Smoking; One Associated With Alcohol Use
http://www.medicalnewstoday.com/articles/129708.php
Researchers who have been following the health of more than 120,000 residents of the Netherlands for more than two decades have found that smoking is associated with two forms of esophageal cancer as well as a form of stomach cancer, and that drinking alcohol is strongly linked to one form of esophageal cancer.

Behavior/Lifestyle Factors Influence Cancer Risk Among The Elderly
http://www.medicalnewstoday.com/articles/129707.php
Behavioral risk factors have a significant effect on cancer risk in the U.S. elderly population, according to research presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.

Brain Tumor Cells Release Tiny Sacs Which Carry Information That May Guide Treatment
http://www.medicalnewstoday.com/articles/129701.php
Microvesicles - tiny membrane-covered sacs - released from glioblastoma cells contain molecules that may provide data that can guide treatment of the deadly brain tumor. In their report in the December 2008 <i>Nature Cell Biology</i>, which is receiving early online release, Massachusetts General Hospital (MGH) researchers describe finding tumor-associated RNA and proteins in membrane microvesicles called exosomes in blood samples from glioblastoma patients.

Barrett's Esophagus May Be Affected By DFMO
http://www.medicalnewstoday.com/articles/129694.php
"While there was a suggestion that DFMO may influence the extent of Barrett's dysplasia, this finding is very preliminary and further study of this agent in a larger number of patients is needed," said Frank A.

Long-Term Vitamin E Or Vitamin C Supplementation Does Not Offer Protectiion From Cancer
http://www.medicalnewstoday.com/articles/129693.php
The Physicians' Health Study II is a large-scale, long-term, randomized clinical trial that included 14,641 physicians who were at least 50 years old at enrollment. These physicians were given 400 IU of vitamin E every other day or its placebo, or 500 mg of vitamin C daily or its placebo.

Blood Exosomes Shown To Contain Tumor Specific Genetic Information For Brain Cancer
http://www.medicalnewstoday.com/articles/129686.php
Tiny vesicles called exosomes released into the bloodstream from aggressive brain tumors contain genetic signatures that may help guide future diagnosis and treatment of this deadly disease. In their report in the December issue of <I>Nature Cell Biology</I> (DOI: 10.

Survey Of Beachgoers' Tanning Habits Should Help Interventions To Prevent Skin Cancer
http://www.medicalnewstoday.com/articles/129660.php
A study published in the November issue of <i>Archives ofDermatology</i> seeks to determine which beachgoers would benefitfrom targeted interventions to reduce skin cancer risk by identifyingsun-protection practices and risk profiles.

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** CERVICAL CANCER / HPV VACCINE News **

No news for this category today.

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** COLORECTAL CANCER News **

Studies To Examine Factors Behind Racial Disparities In Breast, Colon Cancers
http://www.medicalnewstoday.com/articles/129775.php
The following summarizes articles about two cancer studies that examine racial disparities.<ul><li class="AdvisoryBullet">Breast cancer: Researchers from the University of North Carolina's <a href="http://cancer.

Role Of Vitamin D In Cancer Therapy Clarified By Study
http://www.medicalnewstoday.com/articles/129737.php
A colon cancer cell isn't a lost cause. Vitamin D can tame the rogue cell by adjusting everything from its gene expression to its cytoskeleton. In the Nov. 17 issue of the <i>Journal of Cell Biology</i>, Ordóñez-Morán et al.

Calcium May Only Protect Against Colorectal Cancer In Presence Of Magnesium
http://www.medicalnewstoday.com/articles/129695.php
High magnesium intake has been associated with low risk of colorectal cancer. Americans have similar average magnesium intake as East Asian populations. If that were all that were involved, observers might expect both groups to have similar risk for colorectal cancer.

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** LUNG CANCER News **

Why Only Some Former Smokers Develop Lung Cancer
http://www.medicalnewstoday.com/articles/129803.php
Canadian researchers are trying to answer why some smokers develop lung cancer while others remain disease free, despite similar lifestyle changes.Results were presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.

Extending Chemotherapy Improves Control Of Lung Cancer
http://www.medicalnewstoday.com/articles/129752.php
A new Australian study has found that extending the use of chemotherapy in patients with advanced non-small cell lung cancer better controls the disease, as well as providing a modest improvement in survival.

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** LYMPHOMA / LEUKEMIA News **

Cold/Flu Breakthrough Remedy Undergoes NCI-Sponsored Trial In Leukemia Patients: Canada
http://www.medicalnewstoday.com/articles/129834.php
Cancer patients - with their weakened immune systems - are particularly vulnerable when the cold and flu season hits. To help, the U.S. National Cancer Institute (NCI) is sponsoring a landmark trial to see whether a unique Canadian cold remedy - COLD-FX - can help.

Researchers Tackle CLL, Diabetes And Trauma-Hemorrhage - Molecular Medicine, A Bi-Monthly Journal
http://www.medicalnewstoday.com/articles/129718.php
Chronic Lymphocytic Leukemia (CLL) is a disease of the B lymphocytes of the immune system. Under normal conditions, B lymphocytes (or B cells) play an important role in battling infection. CLL is a disease manifested by uncontrolled growth of these B lymphocytes.

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** PROSTATE / PROSTATE CANCER News **

Genetic Risk Factors May Tailor Prostate Cancer Screening Approaches
http://www.medicalnewstoday.com/articles/129805.php
Men with a family history of prostate cancer and African-American men are particularly susceptible to the disease, with a twofold to sevenfold increased risk. Assessing risk in these populations has been difficult.

Growing Number Of Young Prostate Cancer Patients Need 'sexual Rehabilitation'
http://www.medicalnewstoday.com/articles/129757.php
Prostate cancer is being detected and treated at an earlier age, resulting in more cases of erectile dysfunction in younger men. While for many this is a temporary setback, for some it can take much longer and others will never recover their former capability.

Significantly Lower PSA Levels Discovered In Men Who Take Aspirin
http://www.medicalnewstoday.com/articles/129689.php
The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University.

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