Cancer Guide Blog: October 2008

Friday, October 31, 2008

Medical News Today News Alert

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Welcome to today's Medical News Today News Alert containing today's medical news headlines for your chosen categories. You will only receive these alerts when new news is available for your chosen categories.

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** BREAST CANCER News **

'New' Estrogen Receptor Found To Be Key Player In Tamoxifen Resistance
http://www.medicalnewstoday.com/articles/127715.php
Researchers at Georgetown University Medical Center have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug.

Aetna Tackles Quality Issues In Genetic Testing For Breast Cancer - Promoting Evidence-based Approach
http://www.medicalnewstoday.com/articles/127711.php
Aetna (NYSE:AET) is implementing a comprehensive plan to increase the quality of genetic diagnosis and treatment of breast cancer. The company is guiding members and physicians to laboratories that meet national guidelines for genetic testing accuracy.

A Key To Aggressive Breast Cancer Discovered By UC Davis Researchers
http://www.medicalnewstoday.com/articles/127700.php
In trying to find out why HER2-positive breast cancer can be more aggressive than other forms of the disease, UC Davis Cancer Center researchers have surprisingly discovered that HER2 itself is the culprit.

Vigorous Activity Protects Against Breast Cancer
http://www.medicalnewstoday.com/articles/127625.php
Normal-weight women who carry out lots of vigorous exercise are approximately 30% less likely to develop breast cancer than those who don't exercise vigorously. A study of more than thirty thousand postmenopausal American women, reported in BioMed Central's open access journal Breast Cancer Research, has revealed that a sedentary lifestyle can be a risk factor for the disease - even in women who are not overweight.

Grant For Imaging-Agent Research Awarded By Susan G. Komen Breast Cancer Foundation
http://www.medicalnewstoday.com/articles/127595.php
Clemson University researchers developing imaging agents to allow a new method of detecting breast cancers have received $180,000 from the Susan G. Komen Breast Cancer Foundation. Breast cancer is the second leading cause of cancer deaths in American women.

New Tumor Inhibitor For Treatment Of Hereditary Breast Cancer Shows Promising Results In Mouse Model
http://www.medicalnewstoday.com/articles/127580.php
Researchers of the Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital used the novel inhibitor AZD2281 to target breast cancer, in which the BRCA1-gene plays a role, in a genetically engineered mouse model.

Symptoms Of Toxicity Are Markers Of Breast Cancer Treatment Success
http://www.medicalnewstoday.com/articles/127574.php
An article published early online and in the December edition of The LancetOncology reports that if breast cancer patients who receive endocrine treatmentdevelop hot flushes, vasomotor symptoms (such as cold and night sweats), andjoint symptoms, then they have a lower likelihood of cancer recurrence.

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** CANCER / ONCOLOGY News **

Identification Of Mechanism, Possible Drug Treatment For Tumors In Neurofibromatosis
http://www.medicalnewstoday.com/articles/127708.php
Researchers studying neurofibromatosis type 1 - a rare disease in which tumors grow within nerves - have found that the tumors are triggered by crosstalk between cells in the nerves and cells in the blood.

Biothera To Present Imprime PGG(R) Clinical Trial Results At The International Society For Biological Therapy Of Cancer
http://www.medicalnewstoday.com/articles/127707.php
Biothera will present the results of two separate Phase I clinical trials evaluating the safety of Imprime PGG®, the company's developmental immunotherapy cancer drug, at the International Society for Biological Therapy of Cancer on Saturday, November 1 in San Diego, Calif.

ERBITUX® Supplemental Biologics License Application For First-Line Recurrent Or Metastatic Head And Neck Cancer Accepted For Priority Review By FD
http://www.medicalnewstoday.com/articles/127704.php
ImClone Systems Incorporated (NASDAQ: IMCL) and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing and review the companies' supplemental Biologics License Application (sBLA) to broaden the indication for ERBITUX® (cetuximab) to include use in combination with platinum-based chemotherapy for the first-line treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN).

Oral Rinses Used For Tracking HPV-Positive Head And Neck Cancers Hold Promise For Screening
http://www.medicalnewstoday.com/articles/127678.php
A study published in the journal Clinical Cancer Research, a journal of the American Association for Cancer Research, validates a non-invasive screening method with future potential for detection of human papillomavirus (HPV)-positive head and neck cancers.

Nutrition Advice For Cancer Patients And Survivors Available In New DVD
http://www.medicalnewstoday.com/articles/127654.php
Good nutrition is vitally important to both cancer patients and cancer survivors in promoting healing and preventing recurrence. Yet this can be a challenge, especially for current patients, for whom eating and drinking is often difficult due to treatment side effects that alter appetite and sense of taste.

The Best Cancer Information For Everyone, For Free - UK
http://www.medicalnewstoday.com/articles/127649.php
From November the award winning information booklets about cancer produced by Cancerbackup, the cancer information charity, will be available free of charge to all clinicians, for the first time.

Gleevec Holds Potential As First Drug To Successfully Treat Neurofibromatosis, IU Scientists Report
http://www.medicalnewstoday.com/articles/127626.php
Researchers at the Indiana University School of Medicine report that the anti-cancer drug Gleevec holds out promise to become the first effective treatment for neurofibromatosis, a genetic disease that has resisted treatments until now.

More Than The Physical Act: Sexuality Issues In Oncology - Podcast
http://www.medicalnewstoday.com/articles/127616.php
Discussing sexuality with cancer patients undergoing chemotherapy transcends the physical act: issues of body image; fertility; relationships and self esteem arise. In this week's podcast, Michael Bouwman discusses with Marie Lavin the effect that Chemotherapy has on a patient's sexuality and health care responses to this issue.

Two Key Processes That Allow Cancer Cells To Change How They Move In Order To Spread Discovered
http://www.medicalnewstoday.com/articles/127609.php
Scientists have discovered the two key processes that allow cancer cells to change the way they move in order to spread through the body, reports leading scientific journal 'Cell' (1).

Frequent Urination Protects Against Bladder Cancer
http://www.medicalnewstoday.com/articles/127579.php
A new study has analysed the effect of urinary frequency on the risk of bladder cancer. The conditions of this research which is published in the latest number of the International Journal of Cancer, show a direct association between the number of times people get up at night to urinate and protection against bladder cancer.

Cancer Requires Support From Immune System To Develop
http://www.medicalnewstoday.com/articles/127575.php
Tumors that grow around nerves in a rare genetic disease need cooperation from cells from the immune system in order to grow, reports a team of scientists, including researchers from UT Southwestern Medical Center.

InteRNA Technologies And VU University Medical Center To Develop MicroRNA-Based Diagnostics And Therapeutics For Cancer
http://www.medicalnewstoday.com/articles/127568.php
InteRNA Technologies B.V. and VU university medical center in Amsterdam, VUmc, announce the signing of a framework research agreement to develop microRNA (miRNA)-based diagnostics and therapeutics for cancer using InteRNA's proprietary library of miRNAs.

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** CERVICAL CANCER / HPV VACCINE News **

Gardasil(R) Vaccine Honoured With International Galien Prize For Pharmaceutical Research
http://www.medicalnewstoday.com/articles/127733.php
Gardasil®, the four-type (6,11,16,18) human papillomavirus (HPV) vaccine, has been awarded the 2008 International Galien Prize, a prestigious award for recognising and promoting significant advances in pharmaceutical research which is considered the pharmaceutical industry equivalent of the Nobel Prize.

Cervical Cancer Awareness Week - SOGC Reminds Women About The Importance Of Cervical Cancer Screening And Prevention
http://www.medicalnewstoday.com/articles/127647.php
To recognize Cervical Cancer Awareness Week (Oct. 27-31), the Society of Obstetricians and Gynaecologists of Canada (SOGC) is reminding all Canadian women of the importance of taking proactive steps to prevent cervical cancer, such as receiving regular Pap test screening or HPV vaccination.

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** COLORECTAL CANCER News **

No news for this category today.

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** LUNG CANCER News **

No news for this category today.

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** LYMPHOMA / LEUKEMIA News **

No news for this category today.

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** PROSTATE / PROSTATE CANCER News **

No news for this category today.

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Thursday, October 30, 2008

Medical News Today News Alert

Dear Subscriber,

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** BREAST CANCER News **

Tamoxifen Resistant Breast Cancer New Reason Found
http://www.medicalnewstoday.com/articles/127571.php
A US study found a new way in which breast cancer becomes resistant to tamoxifen, the most widely sold drug for breast cancer prevention and treatment throughout the world. The researchers suggest this could be an early way to spot patients who are not responding to tamoxifen and give doctors time to find an alternative treatment sooner.

Patient Strategies Identified For Managing Symptoms Of Lymphedema
http://www.medicalnewstoday.com/articles/127477.php
An estimated 2 million women in the United States are at risk of developing lymphedema, a condition that involves the chronic and abnormal swelling of the arm, chest, neck and/or back, as a complication of breast cancer treatment.

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** CANCER / ONCOLOGY News **

ImClone Announces ERBITUX(R) Commercial Launch In Canada For Advanced Colorectal Cancer
http://www.medicalnewstoday.com/articles/127555.php
ImClone Systems Incorporated (NASDAQ: IMCL) today announced the commercial launch of ERBITUX® (cetuximab) in Canada for use in the treatment of metastatic colorectal cancer (mCRC). Bristol-Myers Squibb collaborates with ImClone on ERBITUX in North America and is making the product commercially available through its wholly-owned subsidiary Bristol-Myers Squibb Canada.

Cancer Prevention: The Upside To Allergies
http://www.medicalnewstoday.com/articles/127484.php
A new article in the December issue of The Quarterly Review of Biology provides strong evidence that allergies are much more than just an annoying immune malfunction. They may protect against certain types of cancer.

Discovery Of New Eph Receptor Tyrosine Kinase Overexpressed In Gastric Cancer
http://www.medicalnewstoday.com/articles/127456.php
The potential role of Eph receptor and ephrin ligand family in human cancer is receiving increasing attention. Compared with other Eph receptors, EphA4 is distinguished by its ability to bind to both type A ephrins and most type B ephrins.

A Potential Target For The Prevention Or Treatment Of Esophageal Carcinoma
http://www.medicalnewstoday.com/articles/127453.php
Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR.

Candidate Markers For Gastric Cancer
http://www.medicalnewstoday.com/articles/127449.php
The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes. As a result, there is intense interest in applying proteomics to foster a better understanding of cancer processes, develop new biomarkers for diagnosis and early detection of cancer.

Does Diabetes Have A Direct Carcinogenetic Effect?
http://www.medicalnewstoday.com/articles/127448.php
The association of DM2 with solid tumors, and particularly with HCC, has been long suspected and several studies have reported increased mortality rates for neoplastic diseases in patients with DM2.

Severe Gestational Hypertension May Protect Against Testicular Cancer
http://www.medicalnewstoday.com/articles/127446.php
Women who experience severe gestational hypertension may give birth to boys at lower risk for testicular cancer, although the exact reasons why are still unclear, according to a paper published in the November 1, 2008, issue of <a href="http://cancerres.

Jefferson Department Of Surgery Announces New Pancreas Tumor Registry
http://www.medicalnewstoday.com/articles/127419.php
Charles J. Yeo, M.D., Samuel D. Gross Professor and Chair, Department of Surgery at Jefferson Medical College of Thomas Jefferson University, announces the establishment of the new Jefferson Pancreas Tumor Registry (JPTR).

Rexin-G Returns To The Big Apple: Clinical Trials For Pancreatic Cancer And Breast Cancer Open In Manhattan
http://www.medicalnewstoday.com/articles/127407.php
Epeius Biotechnologies Corporation announced the expansion of clinical trials using intravenous Rexin-G for pancreatic cancer and breast cancer in Manhattan, New York. Rexin-G is the world's first tumor-targeted genetic medicine that is designed to seek out and destroy both primary tumors and metastatic cancers that have spread throughout the body.

DPH Announces Database On Cancer Incidence And Mortality Rates For Connecticut Now Available Online
http://www.medicalnewstoday.com/articles/127400.php
The Connecticut Department of Public Health (DPH) today announced an online database on cancer incidence and mortality rates for Connecticut and each of the eight counties in Connecticut. The "Cancer Incidence and Mortality in Connecticut" resource produces tables with cancer rates for each of the state's counties, and county maps colored according to the range of cancer rates for each type of cancer.

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** CERVICAL CANCER / HPV VACCINE News **

No news for this category today.

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** COLORECTAL CANCER News **

No news for this category today.

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** LUNG CANCER News **

No news for this category today.

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** LYMPHOMA / LEUKEMIA News **

No news for this category today.

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** PROSTATE / PROSTATE CANCER News **

No news for this category today.

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Wednesday, October 29, 2008

Medical News Today News Alert

Dear Subscriber,

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** BREAST CANCER News **

Ikonisys Receives FDA Clearance For Non-Invasive, HER-2 Breast Cancer Test
http://www.medicalnewstoday.com/articles/127374.php
Ikonisys, a leading provider of next generation, non-invasive, cell-based diagnostic solutions, announced today that it has received clearance from the U.S. Food and Drug Administration (FDA) for its oncoFISH her2 test.

New Report Shows Media Coverage Of Lung Cancer Is Increasing, And Increasingly Negative
http://www.medicalnewstoday.com/articles/127361.php
CancerCare has announced that despite an overall increase in news reporting on lung cancer, the overall tone of lung cancer media coverage has become significantly more negative. "How the U.S.

Phase 1 Clinical Trial Of PV-10 In Recurrent Breast Cancer Complete, Says Provectus Pharmaceuticals
http://www.medicalnewstoday.com/articles/127343.php
Provectus Pharmaceuticals, Inc. (OTC BB: PVCT), a development-stage oncology and dermatology biopharmaceutical company, announced that it has successfully completed its Phase 1 clinical trial of PV-10 in the treatment of recurrent breast carcinoma.

Breast Cancer Radiation Device Prompts Concerns Over FDA Quick-Review Process
http://www.medicalnewstoday.com/articles/127254.php
 A device to treat breast cancer that was cleared for use in the U.S. under <A href="http://www.fda.gov/" target=_new>FDA</A>'s quick-review process raises concerns from critics that the agency is not thoroughly vetting some experimental medical devices before approval, the <A href="http://www.

Breast Cancer - IU School Of Medicine Researchers Earn Susan G. Komen For The Cure Grants
http://www.medicalnewstoday.com/articles/127224.php
Faculty members of the Indiana University School of Medicine have been awarded research grants from Susan G. Komen for the Cure. John Foley, Ph.D., David Gilley, Ph.D., and Hiromi Tanaka, Ph.

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** CANCER / ONCOLOGY News **

Published Preclinical Study Shows Receptor BioLogix's Pan-HER Ligand Trap Has Broad Anti-Cancer Activity
http://www.medicalnewstoday.com/articles/127371.php
Receptor BioLogix, Inc., today announced that a new publication in the journal Molecular Cancer Therapeutics1 confirms the broad anti-cancer potential of its pan-HER (human EGF receptor) ligand traps, which are novel fusion proteins designed to significantly improve the response rate and increase the survival of patients with HER-related cancers.

Onconova Announces Publication Of Positive Phase I Results For Lead Anticancer Compound In Journal Of Clinical Oncology
http://www.medicalnewstoday.com/articles/127368.php
Onconova Therapeutics, Inc. announced today the publication of positive results from a first-in-human Phase I clinical trial of its lead anticancer drug, ON 01910.Na, in advanced refractory solid tumors.

Merck Serono And Lpath Form Alliance For ASONEP, A Phase I Monoclonal Antibody, Across All Indications
http://www.medicalnewstoday.com/articles/127359.php
Merck Serono, a division of Merck KGaA, announced today that it has entered a worldwide alliance with Lpath, Inc. (OTCBB:LTPN) of the United States to develop and commercialize ASONEP, a Phase I monoclonal antibody currently being evaluated for the treatment of various cancer types.

Cancer Drug Development Could Benefit From Improved Rodent Trials
http://www.medicalnewstoday.com/articles/127334.php
Better design of rodent trials could reduce the cost and time required for cancer drug development, according to a commentary in the October 28 online issue of the Journal of the National Cancer Institute.

News From The Journal Of The National Cancer Institute, Oct. 28
http://www.medicalnewstoday.com/articles/127287.php
Skewed X Inactivation in BRCA1 Mutation CarriersOne X chromosome is more frequently silenced than the other X chromosome in women who carry mutations in the BRCA1 gene, and the skewed X inactivation is associated with a later onset of breast or ovarian cancer in these women.

World First Early Stage Diagnostic Test For Ovarian Cancer
http://www.medicalnewstoday.com/articles/127256.php
There is new hope for women around the world, with the launch of an early detection test for ovarian cancer. The test, developed in Melbourne by HealthLinx scientists in collaboration with ARL Pathology, is called the OvPlex™ Panel and works by identifying whether five biomarkers (proteins) are present in a blood sample.

Cleveland BioLabs Protectan CBLB612 Demonstrates Significant Reduction Of Myelosuppression In Mouse Model Of Chemotherapy
http://www.medicalnewstoday.com/articles/127238.php
Cleveland BioLabs, Inc. (NASDAQ: CBLI) today announced results of a series of studies demonstrating Protectan CBLB612's ability to substantially reduce myelosuppression (the most common rate limiting adverse effect of chemotherapy) caused by a widely used chemotherapeutic drug, cyclophosphamide (Cytoxan, Neosar, CTX).

Nanocenter Offers Promising Non-Invasive Cancer Treatment
http://www.medicalnewstoday.com/articles/127220.php
A team of scientists at Arkansas Nanotechnology Center at UALR (the University of Arkansas at Little Rock) has developed what promises to be a non-invasive method of eradicating cancer cells while reducing the life-threatening side effects of chemotherapy and radiation.

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** CERVICAL CANCER / HPV VACCINE News **

Pivotal Study Of SoftPAP Collector Demonstrates Significant Improvements Over Conventional Collection Technique For PAP Sample
http://www.medicalnewstoday.com/articles/127376.php
CytoCore Inc. (OTCBB:CYOE), the developer of cost-effective, screening systems for early detection of gynecological cancers and sexually transmitted diseases, today announced the data analysis from its 703 patient clinical trial on Adequacy, Efficacy and Safety between the SoftPAP® Collector compared to the standard Spatula/CytoBrush Technique.

Fewer Women Than Ever Before Need Their Cervical Screening Test Repeated, UK
http://www.medicalnewstoday.com/articles/127200.php
Fewer women than ever before are having to give a repeat cervical screening sample because the first proved inadequate; a new report from The NHS Information Centre shows today. Less than 100,000 women had to have a repeat screening in 2007-08, with the rate of inadequate screening samples now at its lowest level ever (2.

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** COLORECTAL CANCER News **

No news for this category today.

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** LUNG CANCER News **

Video-Assisted Thoracic Surgery Offers Comprehensive Cancer Removal Compared To Open Surgery
http://www.medicalnewstoday.com/articles/127348.php
Minimally-invasive surgery for lung cancer called video-assisted thoracic surgery or VATS is a relatively new procedure performed almost exclusively at academic centers. Now, a preliminary study to be presented this month at the annual CHEST meeting in Philadelphia is giving surgeons an early look at its benefits.

New Lung Cancer Research Presented At CHEST 2008
http://www.medicalnewstoday.com/articles/127326.php
#7725YOUNGER PATIENTS WITH LUNG CANCER HAVE BETTER SURVIVALLung cancer in younger patients may exhibit distinct clinical features than lung cancer in older patients, including better survival rates at each disease stage.

News Briefs Highlight Research In Pulmonary, Critical Care And Sleep Medicine At CHEST 2008
http://www.medicalnewstoday.com/articles/127285.php
#7720PATIENTS' HOME PHOTOS HELP IDENTIFY ASTHMA TRIGGERS The use of in-home photography may be a more cost-effective alternative to in-home inspections for identifying asthma and allergy triggers.

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** LYMPHOMA / LEUKEMIA News **

Gemin X Pan Bcl-2 Inhibitor Obatoclax Shows Biological, Clinical Activity In Heavily Pre-Treated Patients With Advanced Chronic Lymphocytic Leukemia
http://www.medicalnewstoday.com/articles/127337.php
Gemin X, a clinical stage biopharmaceutical company developing novel, targeted cancer therapeutics, today announced that one of its lead oncology candidates, obatoclax, has demonstrated biological and anti-cancer activity in heavily pre-treated patients with advanced chronic lymphocytic leukemia (CLL).

New Way To Attack Some Forms Of Leukemia Discovered By Syracuse University Researchers
http://www.medicalnewstoday.com/articles/127301.php
Each year, some 29,000 adults and 2,000 children are diagnosed with leukemia, a form of cancer that is caused by the abnormal production of white blood cells in the bone marrow. Current treatments rely primarily on killing the cancer cells, which also destroys normal cells.

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** PROSTATE / PROSTATE CANCER News **

Reduction In Prostate Specific Antigen Levels Associated With Statin Use
http://www.medicalnewstoday.com/articles/127292.php
Use of cholesterol-lowering statins is associated with a statistically significant decline in prostate specific antigen (PSA) levels, according to a report in the October 28 online issue of the Journal of the National Cancer Institute.

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Tuesday, October 28, 2008

Medical News Today News Alert

Dear Subscriber,

To unsubscribe from our news alerts, or to alter any of your subscription details (name,e-mail address etc) please see
http://www.medicalnewstoday.com/newsalerts.php?changemydetails=y .

----------------------------------------------
** BREAST CANCER News **

Dune Medical Launches US FDA Cleared Clinical Trial For Use Of MarginProbe In Breast Cancer Surgery
http://www.medicalnewstoday.com/articles/127139.php
Dune Medical Devices, Ltd. today announced the launch of a pivotal clinical trial of the MarginProbe™ intraoperative, real-time, positive margin detection system, following U.S. Food and Drug Administration (FDA) investigational device exemption (IDE) approval of its protocol during breast cancer surgery.

Department Of Health Research Shows Women Are Unaware Of Link Between Alcohol And Breast Cancer Risk
http://www.medicalnewstoday.com/articles/127053.php
New research from the Department of Health's Know Your Limits campaign reveals that the vast majority of UK women (82%) don't realise alcohol consumption can increase the risk of developing breast cancer.

Breakthrough Breast Cancer's Response To Better Cancer Care, UK
http://www.medicalnewstoday.com/articles/127051.php
Audrey Birt, Breakthrough Breast Cancer's Director for Scotland says: "Breakthrough Breast Cancer welcomes the publication today of Better Cancer Care. It's now essential that clear plans are put in place to ensure the recommendations in this report are implemented as soon as possible.

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** CANCER / ONCOLOGY News **

"Cancer Research" Journal Publishes Successful Angiogenesis Study Using Optimata's Technology
http://www.medicalnewstoday.com/articles/127178.php
Optimata Ltd., developer of the proprietary Optimata Virtual Patient® technology to navigate drug development, announced today that a scientific paper based on research carried out by company scientists will be published in the prestigious "Cancer Research" Journal 2008; edition 68: (21), on November, 1st 2008.

Enzon's HIF-1 Alpha Antagonist Shows Antitumor Activity
http://www.medicalnewstoday.com/articles/127172.php
Enzon Pharmaceuticals, Inc. (Nasdaq: ENZN) presented data from its pipeline programs at the 2008 EORTC-NCI-AACR (European Organization for Research and Treatment of Cancer-National Cancer Institute-American Association for Cancer Research) annual meeting in Geneva, Switzerland.

November Is Pancreatic Cancer Awareness Month
http://www.medicalnewstoday.com/articles/127087.php
According to the American Cancer Society (ACS), pancreatic cancer is the fourth leading cancer killer in the country, with over 37,000 new cases expected and more than 34,000 deaths by year's end.

Don't Forget The Men In October's Sea Of Pink
http://www.medicalnewstoday.com/articles/127078.php
Pink is all the rage in October as money and awareness are raised for the most common cancer for women (other than skin cancer) during Breast Cancer Awareness month. But what about some attention for one of the most common cancers in men? Prostate cancer is the second leading cause of cancer death in men, according to the American Cancer Society.

Health Communication For At-Risk Populations
http://www.medicalnewstoday.com/articles/127074.php
Health Literacy Month, recognized in October, promotes the importance of ensuring access to understandable health information. According to the National Assessment of Adult Literacy, only 12 percent of adults have proficient health literacy - skills needed to manage their health.

That 'Sticky' Chromosomes Have Role In Kidney Cancer, VAI Researchers Find - Somatic Chromosome Pairing May Play Role In Other Cancers As Well
http://www.medicalnewstoday.com/articles/127059.php
Van Andel Institute (VAI) researchers have found that when chromosomes "stick" together during the cell division process, an outcome known as somatic chromosome pairing, the result in two types of kidney cancer is disruption of a gene critical for cellular response to changes in oxygen levels.

Sunesis Announces Updated Clinical Data Of Voreloxin In Platinum-Resistant Ovarian Cancer
http://www.medicalnewstoday.com/articles/127015.php
Sunesis Pharmaceuticals, Inc. (Nasdaq: SNSS) announced a presentation of updated interim results from an ongoing Phase 2 clinical trial demonstrating that the Company's lead product candidate, voreloxin, shows promising efficacy and safety as a single agent in patients with platinum-resistant ovarian cancer.

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** CERVICAL CANCER / HPV VACCINE News **

British MDs Favor Gardasil For Own Children Despite Government Coverage Of Cervarix
http://www.medicalnewstoday.com/articles/127101.php
 Many British doctors are choosing <A href="http://www.merck.com/" target=_new>Merck</A>'s human papillomavirus vaccine Gardasil for their own children over <A href="http://www.gsk.com/" target=_new>GlaxoSmithKline</A>'s Cervarix, which was selected by for coverage through Britain's National Health Service, according to a comment by Phil Hammond, a British doctor and media broadcaster, published Friday in the <CITE>British Medical Journal</CITE>, <A href="http://www.

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** COLORECTAL CANCER News **

PhytoMedical's In Vivo Toxicity And Efficacy Tests On Human Colon Cancer Deliver Promising Results
http://www.medicalnewstoday.com/articles/127144.php
PhytoMedical Technologies, Inc. (OTCBB: PYTO) (FWB: ET6), today announced the results of its anti-cancer compound in vivo toxicity and efficacy tests on HCT116 human colon cancer cells was successful.

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** LUNG CANCER News **

No news for this category today.

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** LYMPHOMA / LEUKEMIA News **

The MDS Foundation Supports Vidaza's Recommendation For European Approval
http://www.medicalnewstoday.com/articles/127136.php
The Myelodysplastic Syndromes (MDS) Foundation supports the positive opinion from the European Union's Committee for Medicinal Products for Human Use (CHMP) recommending approval of VIDAZA (azacitidine) for specific types of MDS patients, including those with high-risk MDS, chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML).

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** PROSTATE / PROSTATE CANCER News **

Prostate Cancer Risk Did Not Reduce With Vitamin E And Selenium
http://www.medicalnewstoday.com/articles/127196.php
An initial independent review of data from a study looking at whether selenium and vitamin E supplements prevented prostate cancer found they had no benefit, taken either together or alone.The review of data from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) was funded by the National Cancer Institute (NCI) in the US and other institutes from the National Institutes of Health in the US.

PCA3 Test May Help Distinguish Aggressive Prostate Cancer
http://www.medicalnewstoday.com/articles/127056.php
The number of prostate cancer cases is increasing rapidly. Fortunately not all these tumours need to be operated - some are slow growing or indolent. The question remains: how do we reliably establish which tumour is aggressive and which is not? The answer may well be given by the PCA3 (Prostate Cancer Gene 3) test, a breakthrough in the diagnosis of prostate cancer.

Doctors Test Advanced Tool For Treating Prostate Cancer
http://www.medicalnewstoday.com/articles/127019.php
Leading radiation oncologists are using the TargetScan Touch(TM) system to deliver radioactive seed therapy in the prostate. The innovative technology is based on a motionless probe which stabilizes the prostate during procedures.

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Monday, October 27, 2008

Medical News Today News Alert

Dear Subscriber,

To unsubscribe from our news alerts, or to alter any of your subscription details (name,e-mail address etc) please see
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** BREAST CANCER News **

No news for this category today.

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** CANCER / ONCOLOGY News **

MicroRNAs Make For Safer Cancer Treatments
http://www.medicalnewstoday.com/articles/126976.php
Viruses -- long regarded solely as disease agents -- now are being used in therapies for cancer. Concerns over the safety of these so-called oncolytic viruses stem from their potential to damage healthy tissues.

Sensitive Ultrasound To Spot Early-Stage Cancer
http://www.medicalnewstoday.com/articles/126938.php
European researchers have developed highly sensitive ultrasound equipment that can detect tiny quantities of reflective microbubbles engineered to stick to specific tumour cells. The technique should pick up tumours early and improve patients' chances of survival.

Anticancer Drugs Are Often Used Off-Label In Children And Adults, Particularly For Palliative Care
http://www.medicalnewstoday.com/articles/126929.php
A Review reporting off-label use of anticancer drugs reports that, between 1990 and 2002, the proportion of off-label drug use in children and adults ranged between 6â€¢7% and 33â€¢2%.

Brain Tumour Patients Are Hailing 2008 As The Year For Optimism
http://www.medicalnewstoday.com/articles/126928.php
Scientists in the USA were asked in 2006 to give priority treatment to glioblastoma brain tumours and this week the prestigious <a href="http://www.nature.com/nature/journal/v455/n7216/full/nature07385.

ARIAD Presents Preclinical Data On Kinase Inhibitor, AP24534, Demonstrating Mechanism-Based Activity In Solid Tumors
http://www.medicalnewstoday.com/articles/126927.php
ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today presented, for the first time, results of studies on its investigational, multi-targeted kinase inhibitor - AP24534 - showing anti-tumor activity in preclinical cancer models.

Engineering Viruses As Safe Tools For Cancer Treatment
http://www.medicalnewstoday.com/articles/126893.php
Viruses - long regarded solely as disease agents - now are being used in therapies for cancer. Concerns over the safety of these so-called oncolytic viruses stem from their potential to damage healthy tissues.

Purple GM Tomatoes Could Fight Cancer And Increase Life Span
http://www.medicalnewstoday.com/articles/126892.php
A team of scientists from the UK and other European countries has created a genetically modified (GM) purple tomato that in a pilot test significantly extended the life span of cancer-susceptible mice that were fed the new tomatoes compared to mice that were fed normal tomatoes.

AACR-Prevent Cancer Foundation Award To Be Presented To Meyskens
http://www.medicalnewstoday.com/articles/126881.php
Frank L. Meyskens, Jr., M.D., one of the "fathers" of the field of cancer chemoprevention, has been selected to receive the seventh annual American Association for Cancer Research (AACR)-Prevent Cancer Foundation Award for Excellence in Cancer Prevention Research.

Pediatric Oncology Research Boosted By $330,000 Funding Of Scholar At Case Western Reserve
http://www.medicalnewstoday.com/articles/126869.php
St. Baldrick's Foundation, a non-profit organization dedicated to raising money for childhood cancer research, awarded $330,000 to fund Alex Huang, M.D., Ph.D., of Case Western Reserve University School of Medicine as a St.

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** CERVICAL CANCER / HPV VACCINE News **

National Vaccine Information Center Says Government Denies Gardasil Risks
http://www.medicalnewstoday.com/articles/126924.php
The National Vaccine Information Center (NVIC) is calling on the Centers for Disease Control (CDC) and Food and Drug Administration (FDA) to publicly release the study design, data and names of principal investigators involved in a statement this week maintaining that Gardasil vaccine is safe with no serious side effects.

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** COLORECTAL CANCER News **

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** LYMPHOMA / LEUKEMIA News **

GPC Biotech Presents New Pre-Clinical Data On RGB-286638 Broad-Spectrum Kinase Inhibitor At EORTC-NCI-AACR Meeting
http://www.medicalnewstoday.com/articles/126979.php
GPC Biotech AG (Frankfurt Stock Exchange: GPC, NASDAQ: GPCB) today reported that pre-clinical data on RGB-286638, the Company's multi-targeted protein kinase inhibitor, were presented at the 20th EORTC-NCI-AACR Symposium: Molecular Targets and Cancer Therapeutics in Geneva, Switzerland in a poster entitled, "RGB-286638 is a novel multi-targeted protein kinase inhibitor with activity in chronic myelogenous leukemia (CML) models," (Abstract #578).

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** PROSTATE / PROSTATE CANCER News **

Recovery Of Sexual Function Following Radical Prostatectomy: Self-Reports At Postoperative Year One
http://www.medicalnewstoday.com/articles/126944.php
PHILADELPHIA, PA, USA (UroToday.com) - This was a pilot randomized clinical trial (n=44) in an academic health science center that was to evaluate three approaches to pelvic floor muscle training (PFMT) following radical prostatectomy.

Gene Found Activated In 70% Of Prostate Cancer Cases, Report George Washington University Medical Center Scientists
http://www.medicalnewstoday.com/articles/126943.php
A gene has been found activated in 70% of prostate cancer tumors, the same gene that has been discovered activated in a majority of breast cancer cases, report scientists at the George Washington University Medical Center led by Dr.

Therapeutic Starvation And Autophagy In Prostate Cancer: A New Paradigm For Targeting Metabolism In Cancer Therapy
http://www.medicalnewstoday.com/articles/126899.php
UroToday.com - In the online edition of The Prostate, Robert S. DiPaola and co-investigators reported their research on autophagy. Autophagy is a mechanism of cellular resistance or alternatively cell death.

Prognostic Value Of Her-2/Neu And DNA Index For Progression, Metastasis And Prostate Cancer-Specific Death After Radical Prostatectomy
http://www.medicalnewstoday.com/articles/126898.php
UroToday.com - In the online version of the International Journal of Cancer, Dr. Sumit Isharwal and associates from Johns Hopkins University reported on the prognostic association between the Her-2/neu oncoprotein expression, abnormal DNA content and prostate cancer (CaP) progression.

Does Prostate Growth Confound Prostate Specific Antigen Velocity? Data From The Baltimore Longitudinal Study Of Aging
http://www.medicalnewstoday.com/articles/126897.php
UroToday.com - In the online version of the Journal of Urology, Dr. Stacy Loeb and colleagues reported on the relationship between prostate growth and PSA changes. As background, PSA isoforms, PSA density, and PSA velocity all help to determine if an elevated PSA is due to prostate cancer (CaP) or benign causes.

Reducing Health Disparities At The American Public Health Association 136th Annual Meeting And Exposition
http://www.medicalnewstoday.com/articles/126872.php
Experts from the Center for Minority Health (CMH) at the University of Pittsburgh Graduate School of Public Health are addressing the successes and challenges of reducing health disparities at the American Public Health Association 136th Annual Meeting and Exposition in San Diego, Oct.

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Sunday, October 26, 2008

Medical News Today News Alert

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Inoperable Or Metastatic Tumors - Calando Pharmaceuticals Announces Completion Of IT-101 Phase 1 Clinical Study
http://www.medicalnewstoday.com/articles/126815.php
Calando Pharmaceuticals, a majority-owned subsidiary of Arrowhead Research Corporation (NASDAQ:ARWR), announced today completion of the IT-101 Phase I clinical study conducted at City of Hope in Duarte, California.

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** CERVICAL CANCER / HPV VACCINE News **

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** COLORECTAL CANCER News **

Novel Marker Of Colon Cancer
http://www.medicalnewstoday.com/articles/126729.php
Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide. Until now, several molecules have been reported to play an important role in gastroenterological tumorigenesis and tumor metastasis, but the molecular mechanisms involved tumor development and progression still remain unclear in colon cancer.

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** LUNG CANCER News **

Practice Makes Perfect In Lung Cancer Surgery
http://www.medicalnewstoday.com/articles/126751.php
Patients operated on by surgeons who do not routinely remove cancer from the lungs may be at a higher risk for complications, according to a study conducted by researchers at Duke University Medical Center.

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** LYMPHOMA / LEUKEMIA News **

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Saturday, October 25, 2008

Medical News Today News Alert

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** CANCER / ONCOLOGY News **

Mechanism In Cells That Generate Malignant Brain Tumors May Offer Target For Gene Therapy
http://www.medicalnewstoday.com/articles/126835.php
Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development of these cells from which malignant brain tumors may originate.

Local Research Foundation Achieves Milestone In Fight Against Cancer
http://www.medicalnewstoday.com/articles/126825.php
Almost everyone knows the devastation that cancer brings to families, workplaces and communities, and many Houstonians are aware of well-known local cancer treatment institutions. Few, however, may be familiar with the CHRISTUS Stehlin Foundation for Cancer Research, a nationally recognized leader in cancer research located in Houston, which recently achieved a milestone in their battle against cancer.

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** CERVICAL CANCER / HPV VACCINE News **

Doctor Criticizes NHS Choice Of Cervarix Over Gardasil For HPV
http://www.medicalnewstoday.com/articles/126820.php
A doctor expressed his opinions regarding the human papillomavirus(HPV) vaccination chosen by the United Kingdom for its immunizationprogram, according to an opinion piece released on October 24, 2008 in BMJ.

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Friday, October 24, 2008

Medical News Today News Alert

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Data Demonstrate Significant Effect On Tumor-Stroma Interaction With Infinity's Hedgehog Pathway Inhibitor IPI-926
http://www.medicalnewstoday.com/articles/126818.php
Infinity Pharmaceuticals, Inc. (NASDAQ: INFI) announced that preclinical studies of IPI-926, Infinity's oral Hedgehog pathway inhibitor currently in Phase 1 clinical development, demonstrate that the compound significantly down-regulates Hedgehog signaling in tumor stroma, thereby disrupting the communication process between tumor and stroma, ultimately leading to tumor growth inhibition.

Targeting Tumors With B-RAF Mutations: 2 Drugs Are Better Than 1
http://www.medicalnewstoday.com/articles/126769.php
In a proportion of human solid tumors, in particular melanomas (a form of skin cancer that is often resistant to chemotherapy), inappropriate activation of the MEK/ERK signaling pathway as a result of mutations in the B-RAF gene promotes tumor cell growth and survival.

The FDA Approves Production Process Strategy Of Aplidin(R), New Marine-Derived Anti-Tumor Agent, Proposed By PharmaMar
http://www.medicalnewstoday.com/articles/126754.php
The Food and Drug Administration (FDA) has accepted the proposal made by PharmaMar, of the Zeltia Group for the production process of Aplidin®, a new marine-derived anti-tumor agent, in clinical development for the treatment of hematological and solid tumors.

Erbitux Receives CHMP Positive Opinion For 1st-Line Use In Head And Neck Cancer, Europe
http://www.medicalnewstoday.com/articles/126752.php
Merck Serono, a division of Merck KGaA, announced today that it has received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), to extend the use of the targeted therapy Erbitux® (cetuximab) to include 1st-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN).

SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined With Standard Of Care Chemotherapy
http://www.medicalnewstoday.com/articles/126678.php
SuperGen, Inc. (NASDAQ: SUPG), a pharmaceutical company dedicated to the discovery and development of novel cancer therapies, today presented data on MP-470, its lead product candidate, and four additional posters, at the 20th EORTC-NCI-AACR Symposium on "Molecular Targets and Cancer Therapeutics" in Geneva, Switzerland.

Moffitt Cancer Center Presents The 2nd Biennial Latinos Y El Cancer Educational Symposium - Free Event Will Be In Spanish
http://www.medicalnewstoday.com/articles/126668.php
Moffitt Cancer Center will host the second biennial Latinos y el cancer Educational Symposium November 8 from 9:30 a.m. to 2 p.m. in the <a href="http://www.moffitt.org/site.aspx?spid=36454F19B1044B38808E35ADD1DFF832" target="_blank" rel="nofollow">Vincent A.

Nerviano Medical Sciences Invited By EORTC-NCI-AACR To Present The State-of-the-Art Of Aurora
http://www.medicalnewstoday.com/articles/126645.php
Aurora inhibitors play a key role in cell duplication and are implicated in both the onset and progression of numerous types of tumour. A lecture focusing on Aurora kinase inhibitors will be presented today by Dr.

Proteolix Presents Solid Tumor Clinical Trial Results For Carfilzomib At EORTC-NCI-AACR International Conference
http://www.medicalnewstoday.com/articles/126644.php
Proteolix, Inc., a leader in the discovery and development of novel therapeutics that target protein degradation pathways in cancer and autoimmune diseases, presented positive data from a Phase 1 clinical trial of carfilzomib (PR-171) in patients with advanced solid tumors at the 20th EORTC-NCI-AACR symposium on "Molecular Targets and Cancer Therapeutics" in Geneva, Switzerland.

Positive Preclinical Data Demonstrating Anti-Tumor Activity Of NKTR-105 (PEG-docetaxel) Presented At 20th EORTC-NCI-AACR Conference
http://www.medicalnewstoday.com/articles/126643.php
Nektar Therapeutics (Nasdaq: NKTR) announced that positive preclinical data for NKTR-105 (PEG-docetaxel) was presented at the 2008 EORTC-NCI-AACR (European Organization for Research and Treatment of Cancer-National Cancer Institute-American Association for Cancer Research) Symposium on Molecular Targets and Cancer Therapeutics being held in Geneva, Switzerland.

Mount Sinai Medical Group Surgeons Perform Robotic Cystoprostatectomy For Bladder Cancer
http://www.medicalnewstoday.com/articles/126631.php
In 2007, according to the National Cancer Institute, an estimated 67,100 new cases of bladder cancer will be diagnosed in the United States and 13,750 people will die of the disease. For most men suffering from invasive bladder cancer, the most serious kind, treatment typically involves open surgery to remove the bladder as well as the nearby prostate and reconstruction of an ileum conduit or neobladder to divert urine.

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** CERVICAL CANCER / HPV VACCINE News **

No Link Between Gardasil, Adverse Events, CDC Says
http://www.medicalnewstoday.com/articles/126693.php
 <A href="http://www.cdc.gov/" target=_new>CDC</A> officials on Wednesday said a federal <A href="http://www.cdc.gov/vaccinesafety/vaers/FDA_and_CDC_Statement.htm" target=_new>study</A> of reported deaths and serious adverse effects in girls and women who received <A href="http://www.

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** COLORECTAL CANCER News **

EntreMed's ENMD-2076 Demonstrates Tumor Regression In Human Colon Cancer Model
http://www.medicalnewstoday.com/articles/126642.php
EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, announced the presentation of preclinical data for its Aurora A/angiogenesis kinase inhibitor, ENMD-2076.

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** LUNG CANCER News **

At Former Ohio Uranium-Processing Plant Major Source Of Radon Exposure Overlooked
http://www.medicalnewstoday.com/articles/126792.php
University of Cincinnati (UC) scientists say that a recent scientific study of a now-closed uranium processing plant near Cincinnati has identified a second, potentially more significant source of radon exposure for former workers.

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** LYMPHOMA / LEUKEMIA News **

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** PROSTATE / PROSTATE CANCER News **

Ariad Presents Preclinical Data On Deforolimus And Bicalutamide In Androgen-Independent Prostate Cancer
http://www.medicalnewstoday.com/articles/126680.php
ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today presented preclinical data on the investigational mTOR inhibitor, deforolimus, alone or in combination with the anti-androgen agent, bicalutamide, in models of prostate cancer.

-------------------------------------------------------------

Thursday, October 23, 2008

Medical News Today News Alert

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** BREAST CANCER News **

Metropolitan Chicago Breast Cancer Task Force Reports On Progress Toward Reducing The Black-White Disparity
http://www.medicalnewstoday.com/articles/126530.php
In what is gaining national recognition as a model for citywide collaboration to address racial health care disparities, The Metropolitan Chicago Breast Cancer Task Force delivered its first report to the community, one year after releasing a major report that outlined more than 30 recommendations for action.

Breast Cancer Mortality Gap Grows Between White, Black Women In Chicago, Report Says
http://www.medicalnewstoday.com/articles/126522.php
Chicago black women's mortality rate from breast cancer was 116% higher than that of white women in 2005, according to a new report from the <a href="http://www.sinai.org/urban/summit/index.asp" target="_new">Metropolitan Chicago Breast Cancer Task Force</a>, the <a href="http://www.

New York Times Columnist Discusses Best Practices For Breast Health
http://www.medicalnewstoday.com/articles/126496.php
 The symptoms of breast cancer often are more prevalent than the disease itself, which can make decisions about further testing and treatment difficult, <A href="http://www.nytimes.com/2008/10/21/health/21brod.

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** CANCER / ONCOLOGY News **

Earlier-stage, Localized Renal Cell Carcinoma - Antigenics Submits Oncophage(R) Application For European Approval
http://www.medicalnewstoday.com/articles/126624.php
Antigenics Inc. (NASDAQ: AGEN) today announced the submission of a Marketing Authorization Application (MAA) to the European Medicines Agency (EMEA) requesting approval for Oncophage® in earlier-stage, localized renal cell carcinoma (kidney cancer) under the conditional authorization provision.

ZymoGenetics Presents Interim IL-21 Phase 2 Results In Renal Cell Cancer
http://www.medicalnewstoday.com/articles/126623.php
ZymoGenetics, Inc. (NASDAQ: ZGEN) presented interim results today from a Phase 2 clinical trial evaluating Interleukin 21 (IL-21) in combination with Nexavar® (sorafenib) tablets in patients with metastatic renal cell cancer.

Exelixis Reports Positive Phase 1 Data For PI3K Inhibitor XL147 At EORTC-NCI-AACR Symposium
http://www.medicalnewstoday.com/articles/126622.php
Exelixis, Inc. (Nasdaq:EXEL) today reported interim data from a phase 1 dose-escalation trial of XL147, a novel small molecule inhibitor of phosphoinositide-3 kinase (PI3K), which is implicated in tumor cell proliferation, survival, and resistance to chemotherapy and radiotherapy.

Aileron Advances First Stapled Peptide Drug Candidate That Targets Newly-Discovered BAX Activation Mechanism
http://www.medicalnewstoday.com/articles/126611.php
Aileron Therapeutics announced today that one of its proprietary Stapled Peptide compounds, referred to as "BIM-SAHB" in an article published today in Nature, was shown to uniquely target a new and fundamental activation mechanism of the programmed cell death or "apoptotic" pathway.

PharmaMar Presents New Data Of Zalypsis(R) And Irvalec(R) In Pediatric, Solid Tumours And Lymphoma
http://www.medicalnewstoday.com/articles/126608.php
PharmaMar, a biotechnology company of Zeltia Group, has presented new data on two antitumoral compounds of marine origin, Zalypsis® and Irvalec®, in Phase I trials in clinical development and in vitro studies and with animal models.

For Tumor Detection Bevacizumab Better Than Gold Standard Imaging
http://www.medicalnewstoday.com/articles/126606.php
Geneva, Switzerland: Scientists have developed a new imaging agent that can be used in scanning for tumours, and which gives a much clearer and more precise image than existing methods. The discovery has the potential to revolutionise pre-clinical cancer research and clinical diagnostic practice, and it makes use of compounds that have already been approved for treating patients: the anti-cancer drug bevacizumab (Avastin) and Copper-64, a radioactive copper nuclide, which is approved by the US Food and Drug Administration (FDA) for some clinical trials.

Validation Of Blood Brain Barrier Vector Technology Data Presented At EORTC-NCI-AACR Symposium
http://www.medicalnewstoday.com/articles/126602.php
AngioChem, Inc., a clinical-stage biotechnology company dedicated to creating and developing new drugs to treat brain diseases, has announced that its lead product, ANG1005, is safe and well tolerated in patients with brain cancer treated to date.

Neotropix(R) Announces Presentation Of Relevant Preclinical Results Of NTX-010 In Pediatric Oncology Models
http://www.medicalnewstoday.com/articles/126588.php
Neotropix(R), Inc., a clinical-stage development company focused on neuroendocrine cancer treatments, announced today exciting data from an extensive pediatric preclinical study performed by the National Cancer Institute (NCI) funded Pediatric Preclinical Testing Program on the use of NTX-010 (Seneca Valley Virus-001), a tumor-selective naturally-occurring oncolytic virus.

Scientists Unlock Secret Of Death Protein's Activation - May Lead To Drugs That Force Cancer Cells To Self-destruct
http://www.medicalnewstoday.com/articles/126570.php
Scientists at Dana-Farber Cancer Institute have identified a previously undetected trigger point on a naturally occurring "death protein" that helps the body get rid of unwanted or diseased cells.

Cohort Study Funded By Helmholtz
http://www.medicalnewstoday.com/articles/126549.php
The Helmholtz Association will invest around 20 million euros over the next five years to put together a large-scale, long-term cohort study. The goal of the study will be to illuminate the causes of common health problems like cardiovascular disease, cancer, diabetes and dementia, as well as to identify risk factors and effective methods of prevention.

Donor Cells For Immune Therapy For Patients With Leukaemia
http://www.medicalnewstoday.com/articles/126548.php
In the future, the bone marrow transfer to patients with leukaemia could be more secure. Experiments with mice have shown already that certain cells of the immune system (regulatory T cells or Tregs) can suppress the dangerous side effects resulting from the treatment.

Study Finds BRAF Mutations In Colorectal Cancer Cause Resistance To Anti-EGFR Therapy
http://www.medicalnewstoday.com/articles/126542.php
European researchers have found that metastatic colorectal cancer patients with a mutation in the BRAF gene do not respond to anti-EGFR therapy with cetuximab and panitumumab. The finding could help doctors better identify which patients are likely to benefit from such treatment, which is commonly used as last-effort therapy but only works in a fraction of patients.

Early Trial Of New Multi-Kinase Inhibitor Shows Impressive Activity In Medullary Thyroid Cancer
http://www.medicalnewstoday.com/articles/126541.php
Preliminary trials of a new multi-kinase inhibitor have indicated it has impressive tumour shrinkage activity in patients with a difficult to treat type of thyroid cancer. The results have put the drug's development on a fast track, prompting the accelerated initiation of a large phase III trial.

Cancer Patients' Response To Chemotherapy Improved By Eating Fruit And Vegetables
http://www.medicalnewstoday.com/articles/126531.php
The leading cause of death in all cancer patients continues to be the resistance of tumor cells to chemotherapy, a form of treatment in which chemicals are used to kill cells.Now a study by UC Riverside biochemists that focuses on cancer cells reports that ingesting apigenin - a naturally occurring dietary agent found in vegetables and fruit - improves cancer cells' response to chemotherapy.

Cancer Groups Collaborate For Initiative To Boost Number Of Minority Oncologists
http://www.medicalnewstoday.com/articles/126525.php
<a href="http://cms.komen.org/komen/index.htm" target="_new">Susan G. Komen for the Cure</a> and the <a href="http://www.asco.org/" target="_new">American Society of Clinical Oncology</a> have partnered to create the <a href="http://www.

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** CERVICAL CANCER / HPV VACCINE News **

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----------------------------------------------
** COLORECTAL CANCER News **

Study Published In NEJM Shows K-ras Gene Mutation Status May Affect Response To ERBITUX(R) Treatment
http://www.medicalnewstoday.com/articles/126592.php
ImClone Systems Incorporated (NASDAQ: IMCL) and Bristol-Myers Squibb Company (NYSE: BMY) today announced the publication of study results showing that metastatic colorectal cancer (mCRC) patients with wild-type or "normal" K-ras tumors who were treated with ERBITUX® (cetuximab) plus best supportive care (BSC) had a statistically significant increase in overall survival and progression-free survival compared to those treated with BSC alone.

Response In Advanced Bowel Cancer Predicted By Gene Expression Pattern
http://www.medicalnewstoday.com/articles/126581.php
Geneva, Switzerland: Research by scientists in France has shown for the first time that identifying patterns of gene expression can be used to predict response to treatment in patients with advanced metastatic colorectal cancer.

Poniard Announces Positive Incremental Efficacy And Safety Data From Phase 2 Picoplatin Trial In Patients With Metastatic Colorectal Cancer
http://www.medicalnewstoday.com/articles/126456.php
Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on oncology, announced positive incremental data from its randomized, controlled Phase 2 clinical trial of picoplatin in patients with metastatic colorectal cancer (CRC).

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** LUNG CANCER News **

New Light Shed On Lung Cancer By Large-Scale Genetic Study
http://www.medicalnewstoday.com/articles/126607.php
A multi-institution team, funded by the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH), have reported results of the largest effort to date to chart the genetic changes involved in the most common form of lung cancer, lung adenocarcinoma.

Unraveling The Genetic Picture Of Lung Cancer
http://www.medicalnewstoday.com/articles/126537.php
A study seeking possible cancer genes elucidated the mutations and the genetic pathways activated in the most common form of lung cancer - lung adenocarcinoma - and could lead to improved diagnosis and treatment, said the director of the Baylor College of Medicine Human Genome Sequencing Center that played a major role in the project led by the National Human Genome Research Institute.

Genome Study Finds 26 Lung Cancer Genes
http://www.medicalnewstoday.com/articles/126472.php
US scientists working on the largest study ever to map the genetic changes involved in lung adenocarcinoma have identified 26 genes that are frequently mutated in this most common form of lung cancer, further increasing opportunities for individualized diagnosis and treatment of the country's leading cause of cancer deaths.

Landmark Genomic Study Of Lung Cancer Published In Nature
http://www.medicalnewstoday.com/articles/126470.php
Scientists announced the results of the largest genomic study to date of lung adenocarcinoma, the most common form of lung cancer. Led by researchers from the Broad Institute of Harvard and MIT, Dana-Farber Cancer Institute, and other research institutions nationwide, the collaborative study unearthed a variety of genetic alterations in patient tumors and pinpointed 26 frequently altered genes more than doubling the number already linked to the disease.

Scientists Find New Genes Linked To Lung Cancer
http://www.medicalnewstoday.com/articles/126468.php
Working as part of a multi-institutional collaboration, scientists at Washington University School of Medicine in St. Louis have assembled the most complete catalog to date of the genetic changes underlying the most common form of lung cancer.

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** LYMPHOMA / LEUKEMIA News **

Potential Reversal Of Leukemia By Silencing A Protein
http://www.medicalnewstoday.com/articles/126596.php
Blocking the signals from a protein that activates cells in the immune system could help kill cells that cause a rare form of blood cancer, according to physicists and oncologists who combined computer modeling and molecular biology in their discovery.

Link Between Gene Variations And Cancer Survival Revealed By U Of MN Study
http://www.medicalnewstoday.com/articles/126552.php
Scientific research shows that certain genes can influence a person's likelihood to contract particular diseases, cancer for example. New research at the Masonic Cancer Center, University of Minnesota demonstrates that genetic markers may also show a person's likelihood to survive the disease.

Link Between Gene Variations And Cancer Survival Revealed By U Of MN Study
http://www.medicalnewstoday.com/articles/126551.php
Scientific research shows that certain genes can influence a person's likelihood to contract particular diseases, cancer for example. New research at the Masonic Cancer Center, University of Minnesota demonstrates that genetic markers may also show a person's likelihood to survive the disease.

Socioeconomic Status Plays Role In Whether Patients Receive Appropriate Treatment For Non-Hodgkin Lymphoma, Study Finds
http://www.medicalnewstoday.com/articles/126521.php
Socioeconomic factors such as income and education appear to affect whether people with non-Hodgkin lymphoma receive appropriate treatment, according to a study in the journal <cite>Cancer</cite>, <a href="http://www.

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** PROSTATE / PROSTATE CANCER News **

Nymox Nears Completion Of New One Year U.S. Study Of Benign Prostatic Hyperplasia Drug
http://www.medicalnewstoday.com/articles/126613.php
Nymox Pharmaceutical Corporation (NASDAQ: NYMX) announced today that the Company's latest multi-center U.S. study of NX-1207, its investigational drug for the treatment of benign prostatic hyperplasia (BPH), is nearing completion.

Poniard Announces Positive Incremental Efficacy And Safety Data From Ongoing Phase 2 Picoplatin Trial In Hormone-Refractory Prostate Cancer
http://www.medicalnewstoday.com/articles/126455.php
Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on oncology, announced positive incremental data from its ongoing Phase 2 clinical trial of picoplatin in combination with docetaxel and prednisone as first-line therapy for metastatic hormone-refractory prostate cancer (HRPC).

-------------------------------------------------------------

Wednesday, October 22, 2008

Medical News Today News Alert

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** BREAST CANCER News **

Nottingham University Hospital Joins National Trial To Improve Breast Cancer Care For Older Women, UK
http://www.medicalnewstoday.com/articles/126367.php
Over half of breast cancers occur in women aged 65 and over and so in a bid to improve treatments and outcomes for women in this age-group, researchers at Nottingham University Hospitals NHS Trust (NUH) have joined a national research trial which will provide fresh hope for millions of women diagnosed with breast cancer.

3-D Doppler Ultrasound Helps Identify Breast Cancer
http://www.medicalnewstoday.com/articles/126351.php
Three-dimensional (3-D) power Doppler ultrasound helps radiologists distinguish between malignant and benign breast masses, according to a new study being published in the November issue of Radiology.

Peregrine Pharmaceuticals Reports Progress In Its Phase II Trial Of Bavituximab Plus Docetaxel In Patients With Advanced Breast Cancer
http://www.medicalnewstoday.com/articles/126276.php
Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM), a clinical stage biopharmaceutical company developing monoclonal antibodies for cancer and serious viral infections, announced that updated preliminary data from the first stage of its Phase II trial evaluating bavituximab in combination with docetaxel showed that 10 of 14 (71%) evaluable breast cancer patients achieved an objective tumor response according to RECIST criteria.

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** CANCER / ONCOLOGY News **

Argos Therapeutics Publishes Approach To Generating High-Avidity Cytotoxic T Cells With Dendritic Cell-Based Immunotherapy
http://www.medicalnewstoday.com/articles/126435.php
Argos Therapeutics today announced the publication of a paper in the October 15th issue of the Journal of Immunonology demonstrating that the Company's proprietary RNA-electroporated dendritic cells generate high-avidity cytotoxic T cells (CTL) in vitro that are able to destroy cells expressing their target antigens.

Neotropix® Announces Presentation Of Relevant Preclinical Results Of NTX-010 In Pediatric Oncology Models
http://www.medicalnewstoday.com/articles/126426.php
Neotropix®, Inc., a clinical-stage development company focused on neuroendocrine cancer treatments, announced today exciting data from an extensive pediatric preclinical study performed by the National Cancer Institute (NCI) funded Pediatric Preclinical Testing Program on the use of NTX-010 (Seneca Valley Virus-001), a tumor-selective naturally-occurring oncolytic virus.

Boehringer Ingelheim's Promising New Data For Potentially First In Class Plk1 Inhibitor
http://www.medicalnewstoday.com/articles/126362.php
Boehringer Ingelheim's most promising new cell cycle kinase inhibitor and potentially first-in-class compound, BI 6727, has shown encouraging results in a phase I clinical trial in patients with advanced tumours who have failed to respond to other treatments.

Chronic Inflammation Can Help Nurture Skin Cancer, Study Shows
http://www.medicalnewstoday.com/articles/126357.php
Inflammation, a frontline defense against infection or disease, can help nurture skin cancer, researchers have found.IDO, an enzyme that works like a firefighter to keep inflammation under control, can be commandeered to protect early malignant cells, say Medical College of Georgia researchers studying an animal model of chronic inflammation and skin cancer.

Intimacy And Sexuality After Cancer: Questions Answered And Concerns Addressed
http://www.medicalnewstoday.com/articles/126327.php
Today The Women's Sexual Health Foundation (TWSHF) released an issue of the Women's Sexual Health Foundation Journal devoted entirely to women's sexuality and cancer, a topic the Foundation frequently addresses with healthcare professionals, cancer patients and survivors.

New Way Of Inhibiting The Cell Cycle Shows Promise In Cancer Patients In A Phase I Clinical Trial
http://www.medicalnewstoday.com/articles/126321.php
A new anti-cancer compound that works by blocking a part of the cell's machinery that is crucial for cell division has shown promising results in a phase I clinical trial in patients who have failed to respond to other treatments.

Crossing The Blood-brain Barrier: Scientists Develop New Drug Delivery System For Brain Cancers And Other, Hard-to-treat Diseases Of The CNS
http://www.medicalnewstoday.com/articles/126320.php
Scientists have developed a new drug delivery system that is capable of crossing the blood-brain barrier to reach and kill cancer cells in the brain, according to research presented at the 20th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Geneva today (Wednesday 22 October).

Bevacizumab Can Be Used To Detect/diagnose Tumours In Animal Models Using PET/CT Imaging: Results Better Than Current 'gold Standard' Method
http://www.medicalnewstoday.com/articles/126319.php
Scientists have developed a new imaging agent that can be used in scanning for tumours, and which gives a much clearer and more precise image than existing methods. The discovery has the potential to revolutionise pre-clinical cancer research and clinical diagnostic practice, and it makes use of compounds that have already been approved for treating patients: the anti-cancer drug bevacizumab (Avastin) and Copper-64, a radioactive copper nuclide, which is approved by the US Food and Drug Administration (FDA) for some clinical trials.

Researchers Identify Pattern Of Gene Expression That Can Predict How Patients With Advanced Bowel Cancer Will Respond To Treatment
http://www.medicalnewstoday.com/articles/126318.php
Research by scientists in France has shown for the first time that identifying patterns of gene expression can be used to predict response to treatment in patients with advanced metastatic colorectal cancer.

Assessing The Quality Of Phase I Clinical Trial Abstracts Submitted To The EORTC-NCI-AACR And ASCO Meetings
http://www.medicalnewstoday.com/articles/126317.php
Researchers have developed a method of assessing the quality of phase I clinical trial abstracts submitted to two different oncology conferences: EORTC-NCI-AACR (ENA) [1] and American Society of Clinical Oncology (ASCO).

Garvan And St Vincent's To Build $100 Million Australian Cancer Centre, Australia
http://www.medicalnewstoday.com/articles/126303.php
The Garvan Institute of Medical Research and St Vincents & Mater Health Sydney will today announce plans to jointly establish a new $100 million Cancer Centre within the St Vincent's Research Precinct.

America's Top Doctors For Cancer Recognizes 20 IU School Of Medicine Physicians
http://www.medicalnewstoday.com/articles/126302.php
Twenty physicians with the Indiana University School of Medicine have been recognized as the best in their field. The 20 are among 25 in Indiana included in the most recent edition of America's Top Doctors for Cancer.

Access Pharmaceuticals Presents ProLindac(TM) Data At The AACR-NCI-EORTC Symposium 2008
http://www.medicalnewstoday.com/articles/126277.php
ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) announced that three posters describing significant recent results of the company's proprietary polymer DACH platinum prodrug, ProLindac, in clinical and preclinical studies are being presented this week at a major international oncology conference held in Geneva, Switzerland.

Rare Peptide Segments Are Found Significantly More Often In Proto-Oncoproteins Than Control Proteins: Implications For Immunology And Oncology
http://www.medicalnewstoday.com/articles/126269.php
There is some evidence to suggest that peptide segments that are found rarely or never in the host proteome play a role in the immune response to disease-related proteins, both those derived from microbes and those derived from the host itself.

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** CERVICAL CANCER / HPV VACCINE News **

New MRI Technique May Identify Cervical Cancer Early
http://www.medicalnewstoday.com/articles/126350.php
Using high-resolution magnetic resonance imaging (MRI) with a special vaginal coil, a technique to measure the movement of water within tissue, researchers may be able to identify cervical cancer in its early stages, according to a new study being published in the November issue of Radiology.

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** COLORECTAL CANCER News **

No news for this category today.

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** LUNG CANCER News **

No news for this category today.

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** LYMPHOMA / LEUKEMIA News **

No news for this category today.

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** PROSTATE / PROSTATE CANCER News **

Medivation Announces Presentation Of 24-Week Clinical Data Of MDV3100 In Castration-Resistant Prostate Cancer Patients
http://www.medicalnewstoday.com/articles/126441.php
Medivation, Inc. (Nasdaq: MDVN) today announced the presentation of new data from an ongoing Phase 1-2 clinical trial demonstrating that the Company's novel androgen receptor antagonist MDV3100 continues to show promising safety and efficacy results.

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